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Merck
CN

MAK077

Uric Acid Assay Kit

sufficient for 100 colorimetric or fluorometric tests

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric or fluorometric tests

detection method

colorimetric, fluorometric

relevant disease(s)

endocrinological disorders, diabetes; cardiovascular diseases; rheumatological diseases; genitourinary disorders

storage temp.

−20°C

General description

In humans and primates, uric acid is the end product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and excreted in urine. High serum levels of uric acid, hyperuricemia, are associated with insulin resistance, cardiovascular disease, and gout. The mechanisms leading to hyperuricemia are typically either increased uric acid production or decreased urine excretion. Increased serum uric acid may be a marker of renal disease.

Application

Uric Acid Assay Kit has been used
  • to determine the uric acid content in human adipose-derived stem cell culture supernatant
  • to measure serum uric acid level in order to analyse kidney function in rat models
  • to determine the uric acid concentration in serum and to study the e antiinflammatory effects of sunflower head ethanol extract in rats
  • in quantitative analysis of uric acid degradation
Suitable for detecting uric acid in biological samples such as serum and urine. Pretreatment of samples is not required

Biochem/physiol Actions

In this assay, Uric Acid concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the Uric Acid present.


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Health hazard

signalword

Danger

hcodes

Hazard Classifications

Aquatic Chronic 3 - Resp. Sens. 1

Storage Class

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

Regulatory Information

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Effect of humic substances on rumen fermentation, nutrient digestibility, methane emissions, and rumen microbiota in beef heifers.
Terry S A, et al.
Journal of Animal Science (2018)
Gabriel O Ribeiro et al.
Scientific reports, 7(1), 1276-1276 (2017-04-30)
Future growth in demand for meat and milk, and the socioeconomic and environmental challenges that farmers face, represent a "grand challenge for humanity". Improving the digestibility of crop residues such as straw could enhance the sustainability of ruminant production systems.
A Role for Uric Acid in the Progression of Renal Disease.
Kang, D.-H
Journal of the American Society of Nephrology, 12, 2888-2897 (2002)



Global Trade Item Number

SKUGTIN
MAK077-1KT04061834065135