MAK077
Uric Acid Assay Kit
sufficient for 100 colorimetric or fluorometric tests
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric or fluorometric tests
detection method
colorimetric, fluorometric
relevant disease(s)
endocrinological disorders, diabetes; cardiovascular diseases; rheumatological diseases; genitourinary disorders
storage temp.
−20°C
General description
In humans and primates, uric acid is the end product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and excreted in urine. High serum levels of uric acid, hyperuricemia, are associated with insulin resistance, cardiovascular disease, and gout. The mechanisms leading to hyperuricemia are typically either increased uric acid production or decreased urine excretion. Increased serum uric acid may be a marker of renal disease.
Application
Suitable for detecting uric acid in biological samples such as serum and urine. Pretreatment of samples is not required
Uric Acid Assay Kit has been used
- to determine the uric acid content in human adipose-derived stem cell culture supernatant
- to measure serum uric acid level in order to analyse kidney function in rat models
- to determine the uric acid concentration in serum and to study the e antiinflammatory effects of sunflower head ethanol extract in rats
- in quantitative analysis of uric acid degradation
Biochem/physiol Actions
In this assay, Uric Acid concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the Uric Acid present.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 3 - Resp. Sens. 1
Storage Class
10 - Combustible liquids
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
Regulatory Information
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Effect of humic substances on rumen fermentation, nutrient digestibility, methane emissions, and rumen microbiota in beef heifers.
Terry S A, et al.
Journal of Animal Science (2018)
Stephanie A Terry et al.
Frontiers in veterinary science, 6, 308-308 (2019-10-15)
The objective of this study was to examine the effect of a pine enhanced biochar (EB) on rumen fermentation, apparent total tract digestibility, methane (CH4) emissions, and the rumen and fecal microbiome of Angus × Hereford heifers fed a barley
A Role for Uric Acid in the Progression of Renal Disease.
Kang, D.-H
Journal of the American Society of Nephrology, 12, 2888-2897 (2002)
Gabriel O Ribeiro et al.
Scientific reports, 7(1), 1276-1276 (2017-04-30)
Future growth in demand for meat and milk, and the socioeconomic and environmental challenges that farmers face, represent a "grand challenge for humanity". Improving the digestibility of crop residues such as straw could enhance the sustainability of ruminant production systems.
Stephanie A Terry et al.
Journal of animal science, 96(9), 3863-3877 (2018-09-01)
Ruminants play an important role in food security, but there is a growing concern about the impact of cattle on the environment, particularly regarding greenhouse gas emissions. The objective of this study was to examine the effect of humic substances
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