MAK081
ADP Colorimetric Assay Kit II
sufficient for 100 colorimetric tests
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About This Item
NACRES:
NA.84
UNSPSC Code:
12352200
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
hematological disorder; cancer
storage temp.
−20°C
General description
Adenosine diphosphate (ADP) is a nucleoside diphosphate that plays a critical role in energy transfer reactions. ADP is produced from adenosine triphosphate via the action of ATPases. ADP also plays a critical role in platelet function. ADP, stored in platelet-dense granules, is released upon platelet activation where it acts on purinergic receptors to mediate intracellular signaling and platelet aggregation.
Application
ADP Colorimetric Assay Kit II has been used to measure the ADP level in infusion medium and variety of samples, particularly those containing reducing agents that may interfere with oxidase based assays.
Suitable for measuring ADP levels in samples that contain reducing substances, which may interfere with oxidase-based assays. Samples include tissue (liver, muscle, heart etc.) and cell culture (adherent or suspension cells).
Biochem/physiol Actions
The ADP Assay kit provides a simple and direct procedure for measuring ADP in a variety of samples. ADP concentration is determined by a coupled enzyme assay, which results in a colorimetric (450 nm) product proportional to the ADP present.
signalword
Danger
Storage Class
10 - Combustible liquids
wgk
WGK 3
hcodes
Hazard Classifications
Aquatic Chronic 2 - ED ENV 1 - Resp. Sens. 1
Regulatory Information
监管及禁止进口产品
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Alan D M.
Platelets (2012)
Kidney outer medulla mitochondria are more efficient compared to cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment.
Schiffer T A, et al.
American Journal of Physiology: Renal Physiology (2018)
Blockade of adenosine diphosphate receptors P2Y(12) and P2Y(1) is required to inhibit platelet aggregation in whole blood under flow.
Nancy A, et al.
Blood, 98(12), 3340-3345 (2001)
Katherine D.
Chemistry (Weinheim An Der Bergstrasse, Germany) (2016)
Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation.
Al-Sha?er M A, et al.
Journal of Molecular Graphics & Modelling, 62, 213-225 (2015)
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