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Merck
CN

MAK085

Sigma-Aldrich

Lipid Peroxidation (MDA) Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonym(s):

MDA Assay, TBARS Assay, Thiobarbituric Acid Reactive Substances Assay

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
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usage

sufficient for 100 colorimetric or fluorometric tests

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

detection method

colorimetric
fluorometric

relevant disease(s)

endocrinological disorders, diabetes; neurological disorders; cancer; cardiovascular diseases

storage temp.

−20°C

General description

Lipid peroxidation is the degradation of lipids that occurs as a result of oxidative damage and is a useful marker for oxidative stress. Polyunsaturated lipids are susceptible to an oxidative attack, typically by reactive oxygen species, resulting in a well-defined chain reaction with the production of end products such as malondialdehyde (MDA). Lipid peroxidation may contribute to the pathology of many diseases including atherosclerosis, diabetes, and Alzheimer′s.

Application

Lipid peroxidation (MDA) assay kit has been used to determine the levels of malondialdehyde (MDA).
Suitable for the measurement of malondialdehyde (MDA) in a variety of samples including tissue, cells and plasma

Biochem/physiol Actions

In this kit, lipid peroxidation is determined by the reaction of MDA with thiobarbituric acid (TBA) to form a colorimetric (532 nm)/fluorometric (λex = 532/λem = 553 nm) product, proportional to the MDA present.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1C

Storage Class Code

3 - Flammable liquids

Flash Point(F)

57.2 °F - closed cup

Flash Point(C)

14 °C - closed cup


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