MAK131
Formaldehyde Assay
sufficient for 100 fluorometric tests
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 fluorometric tests
detection method
fluorometric
relevant disease(s)
cancer
storage temp.
2-8°C
General description
Formaldehyde is widely employed in industry for a wide range of applications. It acts as a disinfectant and biocide, and is utilized as a tissue fixative and embalming agent. Formaldehyde is a key metabolite produced during normal metabolism and contributes to methylation reactions and protein and nucleic acid synthesis. Increased production of formaldehyde has been observed in many cancer cell lines and increased formaldehyde concentration in urine has been associated with bladder and prostrate cancer.
Application
- Modified Natural Rubber as a Simple Chemical Sensor with Smartphone Detection for Formaldehyde Content in a Seafood Sample.: This article explores the use of modified natural rubber as a chemical sensor, paired with smartphone detection, to measure formaldehyde content in seafood. This approach highlights the potential for accessible and mobile detection systems in food safety applications (Yeerum et al., 2022).
- Optical enzymatic formaldehyde biosensor based on alcohol oxidase and pH-sensitive methacrylic-acrylic optode membrane.: The study develops an optical enzymatic biosensor for formaldehyde, using alcohol oxidase with a pH-sensitive membrane, offering a novel approach for quick and sensitive detection in various analytical applications (Nurlely et al., 2022).
Suitable for the detection of formaldehyde in urine and other biological samples.
Biochem/physiol Actions
The Formaldehyde Assay kit provides a simple and direct procedure for measuring formaldehyde levels in urine and other biological samples. In this assay, formaldehyde is derivatized with acetoacetanilide in the presence of ammonia resulting in a fluorescent (λex = 370/λem = 470 nm) product, proportional to the formaldehyde present.
Features and Benefits
Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - STOT SE 1 - STOT SE 3
target_organs
Eyes,Central nervous system, Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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Related Content
Instructions
Cristina A Nadalutti et al.
Scientific reports, 10(1), 5575-5575 (2020-03-30)
Formaldehyde (FA) is a simple biological aldehyde that is produced inside cells by several processes such as demethylation of DNA and proteins, amino acid metabolism, lipid peroxidation and one carbon metabolism (1-C). Although accumulation of excess FA in cells is
Lysine-specific demethylase 1 in breast cancer cells contributes to the production of endogenous formaldehyde in the metastatic bone cancer pain model of rats.
Liu J, et al.
PLoS ONE, 8(3), e58957-e58957 (2013)
Formaldehyde in the workplace and in the home: exploring its clinical toxicology.
Montanaro A.
Laboratory Medicine, 27(11), 752-758 (2015)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAK131-1KT | 04061834357773 |