MAK258
Hepatic Steatosis Assay Kit
sufficient for 100 colorimetric or fluorometric tests
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.84
application(s)
pharmaceutical
detection method
colorimetric
fluorometric
relevant disease(s)
gastrointestinal diseases
storage temp.
−20°C
General description
Hepatic Steatosis, also known as fatty liver, is a disease characterized by an excessive accumulation of lipid droplets within the liver. This can be caused by multiple factors, including excessive alcohol intake, obesity, and other diseases with abnormal fat metabolism. Hepatic Steatosis is commonly used as a marker to determine the hepatotoxicity of drug candidates.
Application
Evaluate hepatic steatosis, quantify triglycerides, and visualize lipid droplet accumulation in hepatocytes. As well as screen drug candidates for steatotic risk.
Biochem/physiol Actions
The Hepatic Steatosis Kit detects triglyceride accumulation and lipid droplet formation in hepatocytes. The kit can be used to screen and evaluate steatosis risk of drug candidates and to study the mechanism of steatosis development. Chloroquine is included as a positive control for inducing steatosis in liver cells, such as HepG2.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
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