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Merck
CN

N0509

Neurotensin Fragment 1-8

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C46H71N13O14
CAS Number:
Molecular Weight:
1030.13
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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SMILES string

CC(C)CC(NC(=O)C1CCC(=O)N1)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(O)=O

assay

≥97% (HPLC)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... NTS(4922)

Application

Used to identify antibody specificities in cross-reactivity studies.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Y C Lee et al.
Digestive diseases and sciences, 30(2), 129-133 (1985-02-01)
The secretion and metabolism of endogeneous neurotensin-like immunoreactivities after a test meal were studied in five healthy human subjects. Intact neurotensin and the N-terminal metabolic fragment, neurotensin 1-8, were quantified by radioimmunoassay with C- and N-terminally directed antisera in conjunction
W Rowe et al.
Journal of neuroendocrinology, 7(2), 109-117 (1995-02-01)
Central administration of neurotensin (NT) stimulates hypothalamic-pituitary-adrenal (HPA) activity in freely-moving rats. Increases in adrenocorticotropin hormone (ACTH) and corticosterone (B) were observed 15 min following central NT administration and remained elevated for up to 4 h. Of the two NT
P P Rompré et al.
European journal of pharmacology, 341(2-3), 169-172 (1998-05-23)
The effects of medial prefrontal cortex microinjections of 3 nmol/0.5 microl of neurotensin-(1-13), the inactive fragment neurotensin-(1-8), or vehicle on the firing rate of midbrain dopamine neurons were studied in anesthetized rats. Twelve of 19 cells tested with neurotensin-(1-13) showed
M N Castel et al.
Peptides, 10(1), 95-101 (1989-01-01)
The electroencephalographic (EEG) effects of the ICV administration of neurotensin (NT 1-13), NT 1-8 (an inactive neurotensin fragment) and D TYR-11 NT (a long-lasting analog of neurotensin) were studied in rats. In awake rats, NT 1-13 (30 micrograms) and D
G W Bennett et al.
Brain research. Developmental brain research, 111(2), 189-196 (1998-12-05)
Neurotensin-like immunoreactivity (NT-LI) was measured in the di-, tel- and mesencephalon of rats from embryonic day 15 (E15) through birth ( approximately E22) until postnatal day 5 (P5) using radioimmunoassay (RIA) and an N-terminal directed polyclonal antibody. NT-LI and NT

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