N0509
Neurotensin Fragment 1-8
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C46H71N13O14
CAS Number:
Molecular Weight:
1030.13
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Amino Acid Sequence
pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg
Application
Used to identify antibody specificities in cross-reactivity studies.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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P P Rompré et al.
European journal of pharmacology, 341(2-3), 169-172 (1998-05-23)
The effects of medial prefrontal cortex microinjections of 3 nmol/0.5 microl of neurotensin-(1-13), the inactive fragment neurotensin-(1-8), or vehicle on the firing rate of midbrain dopamine neurons were studied in anesthetized rats. Twelve of 19 cells tested with neurotensin-(1-13) showed
W Rowe et al.
Journal of neuroendocrinology, 7(2), 109-117 (1995-02-01)
Central administration of neurotensin (NT) stimulates hypothalamic-pituitary-adrenal (HPA) activity in freely-moving rats. Increases in adrenocorticotropin hormone (ACTH) and corticosterone (B) were observed 15 min following central NT administration and remained elevated for up to 4 h. Of the two NT
M N Castel et al.
Peptides, 10(1), 95-101 (1989-01-01)
The electroencephalographic (EEG) effects of the ICV administration of neurotensin (NT 1-13), NT 1-8 (an inactive neurotensin fragment) and D TYR-11 NT (a long-lasting analog of neurotensin) were studied in rats. In awake rats, NT 1-13 (30 micrograms) and D
Y C Lee et al.
Digestive diseases and sciences, 30(2), 129-133 (1985-02-01)
The secretion and metabolism of endogeneous neurotensin-like immunoreactivities after a test meal were studied in five healthy human subjects. Intact neurotensin and the N-terminal metabolic fragment, neurotensin 1-8, were quantified by radioimmunoassay with C- and N-terminally directed antisera in conjunction
M Schnölzer et al.
Electrophoresis, 17(5), 945-953 (1996-05-01)
Proteins were digested in normal and highly 18O-enriched water using proteases commonly employed for protein sequencing. The extent of 18O incorporation into the resulting peptide fragments was characterized by electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS).
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