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Merck
CN

N0762

Supelco

Nalorphine hydrochloride solution

drug standard, 1.0 mg/mL in methanol

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About This Item

Empirical Formula (Hill Notation):
C19H21NO3 · HCl
CAS Number:
Molecular Weight:
347.84
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
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grade

drug standard

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

1.0 mg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

single component solution

storage temp.

2-8°C

SMILES string

Cl.O[C@H]1C=CC2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45

InChI

1S/C19H21NO3.ClH/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20;/h2-6,12-13,15,18,21-22H,1,7-10H2;1H/t12?,13-,15+,18+,19+;/m1./s1

InChI key

NAHATSPWSULUAA-HWXFZQNOSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Bernadette Hörfarter et al.
Wiener medizinische Wochenschrift (1946), 156(9-10), 275-282 (2006-07-11)
On the basis of a case study, the complex problems of the final stages of a COPD will be demonstrated and discussed. Dyspnea and anxiousness are the primary symptoms. If they can be adequately brought under control by opiates and
Cătălina Lionte et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 111(1), 111-114 (2007-06-29)
Respiratory arrest is a major emergency in medical practice, which implies prompt intervention from the physician assisting such case. Respiratory arrest can be classified into primary respiratory arrest, caused by airway obstruction, decreased respiratory drive, or respiratory muscle weakness and
Josef Deutsch et al.
Wiener medizinische Wochenschrift (1946), 156(9-10), 241-244 (2006-07-11)
Therapy and the handling of dyspnea in the last period of one's life is described and discussed from a case report. A patient with lung cancer and a distinct chronic obstructive pulmonary disease is presented. His coping with increasing dyspnea
R Xie et al.
Pharmaceutical research, 15(4), 570-575 (1998-05-20)
The purpose of the study was to investigate the distribution of codeine across the blood-brain barrier (BBB) in rats by microdialysis (MD). Rats were administered intravenous infusion of codeine in doses of (1) 10 mg/kg, (2) 20 mg/kg for 10
M R Bouw et al.
Pharmaceutical research, 15(11), 1673-1679 (1998-12-02)
To investigate the performance of two alternative retrodialysis recovery methods and to describe the influence of different recoveries on the reliability in estimating unbound extracellular concentrations of morphine. Unbound concentrations of morphine in striatum and in blood were determined by

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