N1141
19-Nor-4-androstene-3,17-dione
Synonym(s):
4-Estrene-3,17-dione
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About This Item
Empirical Formula (Hill Notation):
C18H24O2
CAS Number:
Molecular Weight:
272.38
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
211-995-8
MDL number:
InChI key
JRIZOGLBRPZBLQ-QXUSFIETSA-N
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1
SMILES string
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CCC2=O
drug control
USDEA Schedule IIIN; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
room temp
General description
19-Nor-4-androstene-3,17-dione is an anabolic steroid used in dietary food supplements.
Application
19-Nor-4-androstene-3,17-dione may be used as a reference standard in the determination of 19-nor-4-androstene-3,17-dione in dietary supplements using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
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L Dehennin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 766(2), 257-263 (2002-02-05)
The dietary supplements 19-norandrostenedione and 19-norandrostenediol are potential metabolic precursors of nandrolone. They are considered by law in the United States as prohormones without proven therapeutic, curative or diagnostic properties, and therefore available as over-the-counter drugs. Oral dosages of 0.1-1
P J van der Merwe et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 95(7), 510-511 (2005-09-15)
To determine whether the intake of contaminated nutritional supplements could cause an athlete to fail a dope test. A contaminated nutritional supplement was used, identified in an ongoing study screening over-the-counter nutritional supplements. One capsule of the supplement, containing small
P Diel et al.
Toxicology letters, 177(3), 198-204 (2008-03-08)
One of the most frequently misused steroid precursors (prohormones) is 19-norandrostenedione (4-estrene-3,17-dione, NOR), which is, after oral administration, readily metabolised to nortestosterone, also known as nandrolone (durabolin). In this study we have characterised molecular mechanisms of its action determined its
S Frese et al.
Archives of toxicology, 85(6), 635-643 (2010-10-20)
Both 19-norandrostenedione (estr-4-ene-3,17-dione, NOR) and desoxymethyltestosterone (17alpha-methyl-5alpha-androst-2-en-17beta-ol, DMT or "madol") are 'designer steroids' misused for doping purposes in the bodybuilding scene. We have previously characterized the pharmacological profile of madol and identified potential adverse side effects. The aim of this
Ying Lung Tseng et al.
Journal of analytical toxicology, 29(2), 124-134 (2005-05-21)
Nandrolone is one of the synthetic anabolic steroids banned in sports and has been a popular substance abused by athletes in recent years. One of its major metabolites, 19-norandrosterone (19-NA), has been used as a determinant for drug violations in
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