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Merck
CN

N1773

[Ser2]-Neuromedin C

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C49H72N16O11S
CAS Number:
136058-54-3
Molecular Weight:
1093.26
UNSPSC Code:
12352202
PubChem Substance ID:
24897526
NACRES:
NA.26
MDL number:
MFCD00214338

Key Documents

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Product Name

[Ser2]-Neuromedin C, ≥97% (HPLC)

SMILES string

CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(CO)NC(=O)CN)C(C)C)C(N)=O

InChI

1S/C49H72N16O11S/c1-25(2)13-34(45(72)61-33(42(51)69)11-12-77-6)62-46(73)36(15-29-19-52-23-56-29)59-40(68)21-55-49(76)41(26(3)4)65-43(70)27(5)58-44(71)35(14-28-18-54-32-10-8-7-9-31(28)32)63-47(74)37(16-30-20-53-24-57-30)64-48(75)38(22-66)60-39(67)17-50/h7-10,18-20,23-27,33-38,41,54,66H,11-17,21-22,50H2,1-6H3,(H2,51,69)(H,52,56)(H,53,57)(H,55,76)(H,58,71)(H,59,68)(H,60,67)(H,61,72)(H,62,73)(H,63,74)(H,64,75)(H,65,70)

InChI key

CDSKUMVQOSVSRF-UHFFFAOYSA-N

assay

≥97% (HPLC)

form

solid

composition

Peptide content, ~70%

UniProt accession no.

P07492

storage temp.

−20°C

Quality Level

200

Gene Information

human ... GRP(2922)

Biochem/physiol Actions

[Ser2]-Neuromedin C is a bombesin-like peptide known to inhibit feeding.

Other Notes

Bombesin-like peptide originally isolated from the brain of the European green frog, Rana ridibunda.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Biochemical and Biophysical Research Communications, 178, 529-529 (1991)
Eva Mónika Fekete et al.
Brain research bulletin, 71(4), 386-392 (2007-01-09)
Bombesin-like peptides including gastrin releasing peptide and neuromedin C are known to inhibit feeding. Bombesin receptors have been found in moderate to high densities in the amygdaloid body, which is essentially involved in the regulation of feeding and body weight.

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