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Merck
CN

N2268

Sigma-Aldrich

Nω-Nitro-L-arginine p-nitroanilide hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C12H17N7O5 · HBr
CAS Number:
85697-89-8
Molecular Weight:
420.22
MDL number:
MFCD01318756
UNSPSC Code:
12352200
PubChem Substance ID:
24897564
NACRES:
NA.26

Key Documents

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impurities

≤20% dioxane as solvent of crystallization

storage temp.

−20°C

SMILES string

Br.N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C12H17N7O5.BrH/c13-10(2-1-7-15-12(14)17-19(23)24)11(20)16-8-3-5-9(6-4-8)18(21)22;/h3-6,10H,1-2,7,13H2,(H,16,20)(H3,14,15,17);1H/t10-;/m0./s1

InChI key

VLIUCLVWDVXVTH-PPHPATTJSA-N

Biochem/physiol Actions

Nω-Nitro-L-arginine p-nitroanilide hydrobromide inhibits neuronal NO synthase.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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B Hars
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S Burlet et al.
Neuroscience letters, 226(2), 131-135 (1997-04-25)
A sensor allowing the specific detection of nitric oxide (NO) is reported. Together with differential pulsed voltammetry, it allows the detection of a 650 mV signal either in NO solutions or in the rat frontal cortex. The intraperitoneal (i.p.) administration
J B Su et al.
Circulation, 101(15), 1848-1853 (2000-04-19)
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F Lhuillier et al.
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Direct evidence of nitric oxide (NO) involvement in the regulation of hepatic microcirculation is not yet available under physiological conditions nor in haemorrhagic shock. A laser Doppler flowmetry was used to measure liver perfusion index and a specific NO-sensitive electrode
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