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Merck
CN

N3637

Nle-Arg-Phe amide

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C21H35N7O3
CAS Number:
Molecular Weight:
433.55
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Product Name

Nle-Arg-Phe amide, ≥95% (HPLC)

InChI

1S/C21H35N7O3/c1-2-3-10-15(22)19(30)27-16(11-7-12-26-21(24)25)20(31)28-17(18(23)29)13-14-8-5-4-6-9-14/h4-6,8-9,15-17H,2-3,7,10-13,22H2,1H3,(H2,23,29)(H,27,30)(H,28,31)(H4,24,25,26)/t15-,16-,17-/m0/s1

SMILES string

CCCC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI key

XPMYDYSYRCLZEG-ULQDDVLXSA-N

assay

≥95% (HPLC)

form

solid

storage temp.

−20°C

Biochem/physiol Actions

Nle-Arg-Phe amide is a molluscan cardioexcitatory neuropeptide analog.

Other Notes

FMRF amide analog; molluscan cardioexcitatory neuropeptide analog

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Identification of peptide-like substances in the Placopecten: Possible role in growth and reproduction
Pani, A.K.; Roghani, A.; and Croll, R.P.
Biogenic Amines, 19, 47-67 (2005)
Caroline Perner et al.
Immunity, 53(5), 1063-1077 (2020-10-26)
Dendritic cells (DCs) of the cDC2 lineage initiate allergic immunity and in the dermis are marked by their expression of CD301b. CD301b+ dermal DCs respond to allergens encountered in vivo, but not in vitro. This suggests that another cell in the dermis

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