N5132
N-Nitrosodibutylamine
Synonym(s):
Dibutyl nitrosamine, NDBA
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About This Item
Empirical Formula (Hill Notation):
C8H18N2O
CAS Number:
Molecular Weight:
158.24
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
213-101-1
MDL number:
InChI key
YGJHZCLPZAZIHH-UHFFFAOYSA-N
InChI
1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3
SMILES string
CCCCN(CCCC)N=O
density
0.9 g/mL (lit.)
Packaging
Bulk package
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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Effects of ozonation on mutagenic activity of nitrosamines.
B Fouillet et al.
Bulletin of environmental contamination and toxicology, 52(5), 681-686 (1994-05-01)
Volatile N-nitrosamines in selected Italian cheeses.
A Dellisanti et al.
Bulletin of environmental contamination and toxicology, 57(1), 16-21 (1996-07-01)
M Hirose et al.
Carcinogenesis, 12(10), 1773-1776 (1991-10-01)
The effects of butylated hydroxyanisole (BHA) pretreatment on subsequent low dose N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or N,N-dibutylnitrosamine (DBN) treatment on forestomach or esophageal carcinogenesis were investigated in male F344 rats. Groups of animals were pretreated with 2% BHA or basal diet alone
Mohamed F Ismail et al.
International journal of biological sciences, 5(4), 377-387 (2009-06-13)
Spirulina platensis (SP) is a filamentous cyanobacterium microalgae with potent dietary phyto-antioxidant, anti-inflammatory and anti-cancerous properties. The present study aimed to investigate the chemopreventive effect of SP against rat liver toxicity and carcinogenesis induced by dibutyl nitrosamine (DBN) precursors, and
Neveen Said et al.
The Journal of clinical investigation, 123(2), 751-766 (2013-01-17)
Secreted protein acidic and rich in cysteine (SPARC) has been implicated in multiple aspects of human cancer. However, its role in bladder carcinogenesis and metastasis are unclear,with some studies suggesting it may be a promoter and others arguing the opposite.
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