N6162
Anti-Neuropeptide FF1 Receptor (NPFF1) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-G protein-coupled Receptor 147 (GPR147), Anti-RFamide-related Peptide Receptor OT7T022
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~48 kDa
species reactivity
human
technique(s)
western blot: 1:500-1:1,000 using brain lysate
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NPFFR1(64106)
General description
Neuropeptide FF receptor 1 (NPFF1) is a receptor for the protein RFamide-related peptide-3 (RFRP-3). It is expressed in the ovaries and the gene encoding it is localized on human chromosome 10q21.
Immunogen
peptide corresponding to the C-terminal sequence (amino acids 418-430) and N-terminal sequence (amino acids 1-16) of the NPFF1 protein.
Biochem/physiol Actions
Neuropeptide FF receptor 1 (NPFF1) along with its ligand, prevents gonadotropin signaling.
Physical form
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Regulatory Information
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Identification and characterization of two G protein-coupled receptors for neuropeptide FF.
Bonini JA
The Journal of Biological Chemistry, 275(50), 39324-39331 (2000)
Hajime Oishi et al.
Endocrinology, 153(7), 3435-3445 (2012-06-14)
RFamide-related peptide-3 (RFRP-3), a mammalian ortholog of avian gonadotropin-inhibitory hormone, has pronounced inhibitory effects on reproduction in a number of species. RFRP-3 suppresses gonadotropin release at the hypothalamic and/or pituitary levels; however, increasing evidence also suggests putative functions within the
Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N6162-100UG | 04061833296615 |
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