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N7251

4-Nitrocatechol sulfate dipotassium salt

Name: 4-Nitrocatechol sulfate dipotassium salt
Brand: SIGMA

chromogenic sulphatase substrate, crystalline

Synonym(s):

2-Hydroxy-5-nitrophenyl sulfate, 2-Hydroxy-5-nitrophenyl sulfate dipotassium salt monohydrate, p-Nitrocatechol sulfate dipotassium salt

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About This Item

Linear Formula:

C₆H₃NO₇SK₂

CAS Number:

14528-64-4

Molecular Weight:

311.35

NACRES:

NA.77

PubChem Substance ID:

24897816

UNSPSC Code:

12352200

EC Number:

238-550-0

MDL number:

MFCD00007465

Beilstein/REAXYS Number:

3805018

Form:

crystalline

Quality level:

100

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Properties

Product Name

4-Nitrocatechol sulfate dipotassium salt, crystalline

form

crystalline

Quality Level

100

color

yellow

storage temp.

−20°C

SMILES string

[K+].[K+].[O-]c1ccc(cc1OS([O-])(=O)=O)[N+]([O-])=O

InChI

1S/C6H5NO7S.2K/c8-5-2-1-4(7(9)10)3-6(5)14-15(11,12)13;;/h1-3,8H,(H,11,12,13);;/q;2*+1/p-2

InChI key

CKWWBDCAYRJAJB-UHFFFAOYSA-L

Description

General description

4-Nitrocatechol sulfate is an aromatic sulfate.

Chromogenic sulfatase substrate.

Application

4-Nitrocatechol sulfate dipotassium salt has been used as a substrate in mucopolysaccharidoses VI (MPS VI) analysis. It has also been used to measure the activity of glycosaminoglycan (GAG)-degrading enzymes-arylsulfatase B, and exoglycosidases.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Protocols

Enzymatic Assay of Sulfatase (EC 3.1.6.1.)

Articles

Drug Conjugate Analysis using β-Glucuronidases

Drug conjugate analysis and the enzymatic hydrolysis of glucuronides

Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor.

Jin-Peng Sun et al.

The Journal of biological chemistry, 278(35), 33392-33399 (2003-06-18)

The pathogenic bacteria Yersinia are causative agents in human diseases ranging from gastrointestinal syndromes to bubonic plague. There is increasing risk of misuse of infectious agents, such as Yersinia pestis, as weapons of terror as well as instruments of warfare

Mammalian arylsulfatases A and B: relative rates of hydrolysis of artificial substrates.

D B Thompson et al.

Experientia, 42(2), 150-151 (1986-02-15)

Rodent and bovine arylsulfatase B hydrolyze 4-methylumbelliferyl sulfate (4MUS) 10- to 30-fold more efficiently than arylsulfatase A. Therefore, 4MUS grossly underestimates arylsulfatase A activity in the presence of excess arylsulfatase B.

The convulsive effects of dopamine sulfate conjugates in rat brain.

N T Buu et al.

Life sciences, 29(22), 2311-2316 (1981-11-30)

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Global Trade Item Number

SKU	GTIN
N7251-1G	04061834117872
N7251-100MG	04061832941233
N7251-500MG	04061832941240
N7251-5G	04061834117889