Skip to Content
Merck
CN

Key Documents

View All Documentation

N7382

Nitrosomorpholine

Synonym(s):

NMOR

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C4H8N2O2
CAS Number:
59-89-2
Molecular Weight:
116.12
NACRES:
NA.25
PubChem Substance ID:
24897824
UNSPSC Code:
41116105
MDL number:
MFCD00039710
Form:
solid
Quality level:
100
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

solid

Quality Level

100

SMILES string

O=NN1CCOCC1

InChI

1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2

InChI key

ZKXDGKXYMTYWTB-UHFFFAOYSA-N

Biochem/physiol Actions

Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.

Packaging

Bulk package

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

target_organs

Liver

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 2 - STOT RE 1

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX6070
MKCT1742
MKCR8362
MKCN2923
MKCN2922

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
Wolf D Kuhlmann et al.
International journal of experimental pathology, 87(5), 343-359 (2006-09-13)
Adult hepatocytes and liver-cell progenitors play a role in restoring liver tissue after injury. For the study of progenitor cells in liver repair, experimental models included (a) surgical removal of liver tissue by partial hepatectomy; (b) acute injury by carbontetrachloride;
Jutta Groos et al.
Toxicological sciences : an official journal of the Society of Toxicology, 99(2), 446-454 (2007-07-20)
Within the scope of the Rat Liver Foci Bioassay the model carcinogens N-nitrosomorpholine (NNM), 2-acetylaminoflouren (2-AAF), phenobarbital (PB), and clofibrate (CF) were analyzed concerning their potency and dose-response relationship to induce foci of altered hepatocytes (FAHs), which are known to
Pinar Erkekoglu et al.
Toxicology mechanisms and methods, 20(2), 45-52 (2010-01-27)
Nitrites are ubiquitous environmental contaminants present in drinking water and foods. Nitrosamines can be formed endogenously from nitrate and nitrite and secondary amines or may be present in food, tobacco smoke, and drinking water. The major goal of this work
M Tatsuta et al.
Cancer letters, 119(1), 109-113 (2008-04-01)
The effects of prolonged administration of the diuretic amiloride on hepatocarcinogenesis induced by N-nitrosomorpholine (NNM) and the labeling index of the liver were investigated in male Sprague-Dawley rats. Rats were given drinking water containing NNM for 8 weeks and received
View All Related Papers

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Global Trade Item Number

SKUGTIN
N7382-5ML04061837841224
N7382-1ML04061834117995

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service