N7756
N-Nitrosodimethylamine
Synonym(s):
Dimethylnitrosamine
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About This Item
Linear Formula:
(CH3)2NNO
CAS Number:
Molecular Weight:
74.08
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
200-549-8
MDL number:
vapor pressure
5 mmHg ( 20 °C)
description
Bulk package
refractive index
n20/D 1.437 (lit.)
bp
153 °C/774 mmHg (lit.)
density
1.01 g/mL (lit.)
storage temp.
2-8°C
SMILES string
CN(C)N=O
InChI
1S/C2H6N2O/c1-4(2)3-5/h1-2H3
InChI key
UMFJAHHVKNCGLG-UHFFFAOYSA-N
Biochem/physiol Actions
Induces gastric, liver, kidney and lung cancer in mice and rats.
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Carc. 1B - STOT RE 1
target_organs
Liver
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
141.8 °F - closed cup
flash_point_c
61.0 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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Yu Peng et al.
European journal of clinical investigation, 43(4), 358-368 (2013-02-27)
Fluorofenidone (AKF-PD) is a novel pyridone agent. The purpose of this study is to investigate the inhibitory effects of AKF-PD on dimethylnitrosamine (DMN)-induced liver fibrosis in rats and the involved molecular mechanism related to hepatic stellate cells (HSCs). Wistar rats
Man-Chun Huang et al.
Food chemistry, 138(1), 227-233 (2012-12-26)
A sensitive procedure, microwave-assisted extraction (MAE) coupled dispersive micro solid-phase extraction (D-μ-SPE), was developed to extract N-nitrosodimethylamine (NDMA) and other six volatile N-nitrosamines (NAms) from meat products. Parameters affecting the efficiency of MAE and D-μ-SPE were systematically investigated. For MAE
András P Keszei et al.
The American journal of clinical nutrition, 97(1), 135-146 (2012-11-30)
Dietary N-nitroso compounds and endogenous nitrosation are important carcinogenic factors, but human evidence of their role is scarce for esophageal cancer and inconsistent for gastric cancer. We studied the relation between risks of esophageal and gastric cancer subtypes and dietary