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Merck
CN

N8130

4-Nitrophenyl acetate

esterase substrate, chromogenic, ≥98% (TLC), powder or crystals

Synonym(s):

Acetic acid 4-nitrophenyl ester

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About This Item

Linear Formula:
CH3CO2C6H4NO2
CAS Number:
830-03-5
Molecular Weight:
181.15
Beilstein:
515874
EC Number:
212-593-5
MDL number:
MFCD00007326
UNSPSC Code:
12352204
PubChem Substance ID:
24897853
NACRES:
NA.32

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Product Name

4-Nitrophenyl acetate, esterase substrate

Quality Level

200

Assay

≥98% (TLC)

form

powder or crystals

mp

75-77 °C (lit.)

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3

InChI key

QAUUDNIGJSLPSX-UHFFFAOYSA-N

Gene Information

human ... PON1(5444)

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General description

Chromogenic esterase substrate.

Application

4-Nitrophenyl acetate has been used:
  • to evaluate esterase activity in human embryonic kidney cell line
  • in carbonic anhydrase inhibition assay
  • to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
  • as a substrate to determine carboxylesterase (CES) activity in mouse liver cells
  • to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix

Signal Word

Danger

Hazard Statements

H272,H317,H318

Hazard Classifications

Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9010
BCCF7796
BCBW1104
BCBP8051V
BCBK4587V

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