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N8784

Norcantharidin

solid

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About This Item

Empirical Formula (Hill Notation):
C8H8O4
CAS Number:
29745-04-8
Molecular Weight:
168.15
NACRES:
NA.77
PubChem Substance ID:
24278599
UNSPSC Code:
12352202
MDL number:
MFCD00213361
Form:
solid
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form

solid

SMILES string

O=C1OC(=O)C2C3CCC(O3)C12

InChI

1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2

InChI key

JAABVEXCGCXWRR-UHFFFAOYSA-N

Gene Information

human ... PPP2R5A(5525)

General description

Norcantharidin (NCTD) is a demethylated derivative of cantharidin (CTD).

Application

Norcantharidin has been used in primary cell culture and treatment. It has also been used to treat mice inoculated with Huh7 cells subcutaneously.

Biochem/physiol Actions

Norcantharidin is a potential antitumor agent. Norcantharidin helps to block SK-N-SH neuroblastoma cell growth by stimulating autophagy and apoptosis.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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