N9627
Nicotinic acid hydroxamate
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About This Item
Empirical Formula (Hill Notation):
C6H6N2O2
CAS Number:
Molecular Weight:
138.12
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
form
solid
storage temp.
−20°C
SMILES string
ONC(=O)c1cccnc1
InChI
1S/C6H6N2O2/c9-6(8-10)5-2-1-3-7-4-5/h1-4,10H,(H,8,9)
InChI key
IYCHDNQCHLMLJZ-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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K Sugihara et al.
Xenobiotica; the fate of foreign compounds in biological systems, 30(5), 457-467 (2000-06-30)
1. The hydroxamic acids N-hydroxyphenacetin and N-hydroxy-2-acetylaminofluorene were reduced to the corresponding amides, phenacetin and 2-acetylaminofluorene respectively by rabbit blood supplemented with both NAD(P)H and FAD. These reducing activities were found in erythrocytes but not in plasma, and were sensitive
R A Izydore et al.
Research communications in chemical pathology and pharmacology, 70(3), 307-321 (1990-12-01)
A series of benzo- and dibenzohydroxamic acids were shown to have potent hypolipidemic activity in mice and rats lowering both serum cholesterol and triglyceride levels at 20 mg/kg/day. Selected derivatives lowered tissue lipids, i.e. liver, small intestine and aorta, and
A controlled clinical trial of nicotinohydroxamic acid and neomycin in advanced chronic liver disease.
C Hirayama et al.
Digestion, 25(2), 115-123 (1982-01-01)
K Harada et al.
Research communications in chemical pathology and pharmacology, 49(2), 309-312 (1985-08-01)
The effect of oral administrations of nicotinohydroxamic acid (NHA) and neomycin (NM) in ammonia and urea metabolism were investigated in the rat. NHA and NM lowered the blood ammonia level, and NHA increased urinary excretion of urea and depressed urease
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