N9642
β-(2-Naphthyl)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr amide [Disulfide Bridge: 2–7]
≥97% (HPLC)
Synonym(s):
BIM-23014C
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About This Item
Empirical Formula (Hill Notation):
C54H69N11O10S2
CAS Number:
Molecular Weight:
1096.32
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CC(C)C1NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)Cc5ccc6ccccc6c5
assay
≥97% (HPLC)
storage temp.
−20°C
Gene Information
human ... SSTR1(6751), SSTR4(6754)
mouse ... Sstr3(20607)
Biochem/physiol Actions
sst2 somatostatin receptor agonist.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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C Piwko et al.
Naunyn-Schmiedeberg's archives of pharmacology, 352(6), 607-613 (1995-12-01)
Radioligand binding studies were performed in membranes of rat cerebellum using [125I]-[Tyr3]octreotide ([125I]204-090) to characterize the nature of cerebellar somatostatin receptors. Saturation experiments suggest the presence of a single class of binding sites with high affinity, pKd = 9.53 +/-
J E Taylor et al.
Biochemical and biophysical research communications, 153(1), 81-86 (1988-05-31)
An endocrinologically-potent octapeptide analogue of somatostatin (SRIF), 3-(2-naphthyl)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (BIM-23014 C), was examined for its ability to inhibit the in vitro and in vivo growth of the human small cell lung carcinoma (SCLC) line, NCI-H69. When cultured cells were implanted into
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