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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Product Name
NADase from porcine brain, ≥0.007 unit/mg solid
form
powder
specific activity
≥0.007 unit/mg solid
solubility
insoluble
storage temp.
−20°C
Quality Level
Application
NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.
Biochem/physiol Actions
Nicotinamide has been shown to inhibit NADase activity.
General description
NADase is a glycohydrolase that catalyzes ADP-ribose transfer.
Other Notes
One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.
Physical form
Acetone-dried powder
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
低风险生物材料
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Nicholas Chiorazzi
Hematology. American Society of Hematology. Education Program, 2012, 76-87 (2012-12-13)
Several prognostic markers based on genetic, phenotypic, and molecular characteristics of chronic lymphocytic leukemia (CLL) B cells have emerged in the past decade. The clinical utility of these newer prognostic indicators, alone or in combination with each other and other
Julien Calvo et al.
PloS one, 7(11), e50495-e50495 (2012-12-05)
Hematopoietic stem cells are responsible for the generation of the entire blood system through life. This characteristic relies on their ability to self renew and on their multi-potentiality. Thus quantification of the number of hematopoietic stem cells in a given
K A Wall et al.
The Biochemical journal, 335 ( Pt 3), 631-636 (1998-10-31)
Carba-NAD and pseudocarba-NAD are carbocyclic analogues of NAD+ in which a 2,3-dihydroxycyclopentane methanol replaces the beta-d-ribonucleotide ring of the nicotinamide riboside moiety of NAD+ [Slama and Simmons (1988) Biochemistry 27, 183-193]. These carbocyclic NAD+ analogues, related to each other as
Preparation and Evaluation of Arylazide-Substituted Pyridine Adenine Dinucleotides for Photoaffinity Labeling Experiments
Liu, W., et al.
Photochemistry and Photobiology, 63, 793-799 (1996)
Ding-bao Chen et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 607-612 (2012-11-20)
To study the clinical and histopathologic features, diagnosis, pathogenesis and therapy of post-transplant lymphoproliferative disorders (PTLD). The clinical and pathologic features of 15 cases of PTLD were retrospectively analyzed by light microscopy, immunohistochemistry and in-situ hybridization, according to the updated
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