O005
Nalbuphine hydrochloride
Synonym(s):
17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol
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About This Item
Empirical Formula (Hill Notation):
C21H27NO4 · HCl
CAS Number:
Molecular Weight:
393.90
UNSPSC Code:
12352200
EC Number:
245-549-9
MDL number:
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
InChI
1S/C21H27NO4.ClH/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H/t15-,16+,19-,20-,21+;/m0./s1
InChI key
YZLZPSJXMWGIFH-BCXQGASESA-N
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Brenda L Kick et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 56(5), 534-538 (2017-09-15)
Mice undergo a variety of procedures that necessitate the use of analgesic agents. Opioids are often essential to successful pain management plans, but most are controlled substances, and their use requires appropriate federal and state registrations. Nalbuphine is a potentially
Brian K Flesner et al.
Journal of veterinary internal medicine, 34(5), 2056-2067 (2020-07-11)
Osteosarcoma (OSA) in dogs is an aggressive bone tumor with frequent chemotherapy failure and translational relevance for human health. We hypothesized that dogs with OSA could be treated safely by ex vivo activated T-cells that were generated by autologous cancer
Sarah L Withey et al.
The journal of pain : official journal of the American Pain Society, 19(7), 728-740 (2018-02-27)
Although the clinical application of opioids for pain management is often hindered by undesired behavioral impairment, preclinical assays of antinociception typically do not provide information regarding the behaviorally disruptive effects of opioids that may accompany their antinociceptive effects. To address