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O6254

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid

Name: (<I>R</I>)-(&#8722;)-2-Oxothiazolidine-4-carboxylic acid
Brand: SIGMA

≥98% (titration), suitable for plant cell culture

Synonym(s):

L-(−)-2-Oxothiazolidine-4-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):

C₄H₅NO₃S

CAS Number:

19771-63-2

Molecular Weight:

147.15

NACRES:

NA.26

PubChem Substance ID:

24898032

UNSPSC Code:

12352106

MDL number:

MFCD00066092

Beilstein/REAXYS Number:

4179169

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Properties

Product Name

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid, ≥97% (TLC), ≥98% (titration)

Quality Level

200

assay

≥97% (TLC), ≥98% (titration)

form

(powder to crystals)

technique(s)

cell culture | plant: suitable

color

white to off-white

SMILES string

OC(=O)[C@@H]1CSC(=O)N1

InChI

1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1

InChI key

BMLMGCPTLHPWPY-REOHCLBHSA-N

Description

Application

Artificial elevation of glutathione contents in salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) reduces susceptibility to the powdery mildew pathogen Euoidium longipes.: This study explores the impact of enhanced glutathione levels on resistance to powdery mildew in tobacco plants deficient in salicylic acid, indicating a potential application of R-(−)-2-Oxothiazolidine-4-carboxylic acid in managing plant diseases (Künstler et al., 2020).

Biochem/physiol Actions

2-Oxothiazolidine-4-carboxylic acid augments glutathione and cysteine production.

Storage Class

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Artificial elevation of glutathione contents in salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) reduces susceptibility to the powdery mildew pathogen Euoidium longipes.

A Künstler et al.

Plant biology (Stuttgart, Germany), 22(1), 70-80 (2019-07-10)

The effects of elevated glutathione levels on defence responses to powdery mildew (Euoidium longipes) were investigated in a salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) and wild-type cv. Xanthi plants, where salicylic acid (SA) contents are normal. Aqueous solutions

Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine.

Sandra Hodge et al.

American journal of respiratory cell and molecular biology, 44(5), 673-681 (2010-07-03)

Defective efferocytosis may perpetuate inflammation in smokers with or without chronic obstructive pulmonary disease (COPD). Macrophages may phenotypically polarize to classically activated M1 (proinflammatory; regulation of antigen presentation) or alternatively activated M2 (poor antigen presentation; improved efferocytosis) markers. In bronchoalveolar

Cytotoxicity of chlorhexidine on human osteoblastic cells is related to intracellular glutathione levels.

T-H Lee et al.

International endodontic journal, 43(5), 430-435 (2010-06-04)

To evaluate the mechanisms of cytotoxicity of chlorhexidine (CHX) in human osteoblastic cells in vitro. Cytotoxicity, cell proliferation and collagen synthesis assays were performed to elucidate the toxic effects of CHX on the human osteoblastic cell line U2OS. To determine

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Global Trade Item Number

SKU	GTIN
O6254-5G	04061832424378