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Merck
CN

P0268

Pyridine-2-aldoxime methyl methanesulfonate

Synonym(s):

2-PAM methanesulfonate, 2-PAM methanesulfonate salt, P2S, Pralidoxime mesylate, Pralidoxime mesylate salt, Pralidoxime methanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C7H9N2O · CH3O3S
CAS Number:
Molecular Weight:
232.26
UNSPSC Code:
12352103
EC Number:
205-839-8
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InChI key

WWZYJJGFUIAWNW-UHDJGPCESA-N

InChI

1S/C7H8N2O.CH4O3S/c1-9-5-3-2-4-7(9)6-8-10;1-5(2,3)4/h2-6H,1H3;1H3,(H,2,3,4)/b7-6+;

storage temp.

2-8°C

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Misako Yorimitsu et al.
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 11(1), 9-16 (2012-03-28)
Whole-heart 3-dimensional (3D) late-gadolinium-enhanced magnetic resonance (MR) imaging (WH-LGE) uses respiratory gating combined with acquisition of 3D data for the entire heart in a single scan, which permits reconstruction of any plane with high resolution. We investigated the optimal scan
Enes Elvin Gul et al.
Cardiovascular toxicology, 12(3), 263-265 (2012-04-25)
Organophosphate pesticides have emerged as a common cause of poisoning, particularly in developing countries. The most common electrocardiographic abnormalities observed in organophosphate poisoning are sinus tachycardia, QT interval prolongation, and, very rarely, ventricular arrhythmias. We report a case of organophosphate
Diabetic ketoacidosis: an uncommon manifestation of pesticide poisoning.
Krishnan Swaminathan et al.
Diabetes care, 36(1), e4-e4 (2012-12-25)
A Bayir et al.
Human & experimental toxicology, 32(1), 45-52 (2012-10-13)
The aim of this study was to examine the effects of ubiquinone (CoQ10) on heart tissue and erythrocytes in acute organophosphate poisoning (AOP). A total of 20 rabbits were divided into three groups: sham (n = 8), pralidoxime (PAM) +
Robert S Hoffman et al.
Disaster medicine and public health preparedness, 6(1), 20-25 (2011-11-30)
Oximes such as pralidoxime (2-PAM) are essential antidotes for life-threatening organophosphate poisoning. Unfortunately, oximes are expensive, have limited use, and have short shelf lives. As such, maintaining large stockpiles in preparation for terrorist activity is not always possible. We have

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