P0268
Pyridine-2-aldoxime methyl methanesulfonate
Synonym(s):
2-PAM methanesulfonate, 2-PAM methanesulfonate salt, P2S, Pralidoxime mesylate, Pralidoxime mesylate salt, Pralidoxime methanesulfonate
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About This Item
Empirical Formula (Hill Notation):
C7H9N2O · CH3O3S
CAS Number:
Molecular Weight:
232.26
UNSPSC Code:
12352103
EC Number:
205-839-8
storage temp.
2-8°C
InChI
1S/C7H8N2O.CH4O3S/c1-9-5-3-2-4-7(9)6-8-10;1-5(2,3)4/h2-6H,1H3;1H3,(H,2,3,4)/b7-6+;
InChI key
WWZYJJGFUIAWNW-UHDJGPCESA-N
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Sumika Nagase et al.
Clinica chimica acta; international journal of clinical chemistry, 416, 72-79 (2012-12-01)
Drugs sometimes alter the results of clinical laboratory tests. We examined the effects of pralidoxime (PAM) salts, a medicine used to treat organophosphorus poisoning, on clinical laboratory test results for the first time. The effects of PAM salts on glucose
Robert S Hoffman et al.
Disaster medicine and public health preparedness, 6(1), 20-25 (2011-11-30)
Oximes such as pralidoxime (2-PAM) are essential antidotes for life-threatening organophosphate poisoning. Unfortunately, oximes are expensive, have limited use, and have short shelf lives. As such, maintaining large stockpiles in preparation for terrorist activity is not always possible. We have
Marielle Wandhammer et al.
Chemico-biological interactions, 203(1), 19-23 (2012-08-28)
Organophosphorus nerve agents irreversibly inhibit cholinesterases. Phosphylation of the catalytic serine can be reversed by the mean of powerful nucleophiles like oximes. But the phosphyl adduct can undergo a rapid spontaneous reaction leading to an aged enzyme, i.e., a conjugated
Enes Elvin Gul et al.
Cardiovascular toxicology, 12(3), 263-265 (2012-04-25)
Organophosphate pesticides have emerged as a common cause of poisoning, particularly in developing countries. The most common electrocardiographic abnormalities observed in organophosphate poisoning are sinus tachycardia, QT interval prolongation, and, very rarely, ventricular arrhythmias. We report a case of organophosphate
Diabetic ketoacidosis: an uncommon manifestation of pesticide poisoning.
Krishnan Swaminathan et al.
Diabetes care, 36(1), e4-e4 (2012-12-25)
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