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Merck
CN

P1134

Porphobilinogen

powder

Synonym(s):

5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O4
CAS Number:
487-90-1
Molecular Weight:
226.23
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
24898159
EC Number:
207-666-3
Beilstein/REAXYS Number:
220051
MDL number:
MFCD00005224

Key Documents

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Product Name

Porphobilinogen, powder

InChI key

QSHWIQZFGQKFMA-UHFFFAOYSA-N

InChI

1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)

SMILES string

NCc1[nH]cc(CCC(O)=O)c1CC(O)=O

assay

≥96% (HPLC)

form

powder

solubility

1 M NH4OH: 10 mg/mL

storage temp.

−20°C

Quality Level

200

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Biochem/physiol Actions

Intermediate in the biosynthesis of heme.

Preparation Note

Enzymatically prepared.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000514167
0000514167
0000505308
0000504188
0000504188

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Cilly Bernardette Schnider et al.
Frontiers in cellular and infection microbiology, 10, 464-464 (2020-10-06)
An important component in host resistance to malaria infection are inherited mutations that give rise to abnormalities and deficiencies in erythrocyte proteins and enzymes. Understanding how such mutations confer protection against the disease may be useful for developing new treatment
Tijana Jokic et al.
Analytical chemistry, 84(15), 6723-6730 (2012-06-29)
In this study, a series of new BF(2)-chelated tetraarylazadipyrromethane dyes are synthesized and are shown to be suitable for the preparation of on/off photoinduced electron transfer modulated fluorescent sensors. The new indicators are noncovalently entrapped in polyurethane hydrogel D4 and
Takuya Myochin et al.
Journal of the American Chemical Society, 134(33), 13730-13737 (2012-07-27)
Near-infrared (NIR) fluorescence probes are especially useful for simple and noninvasive in vivo imaging inside the body because of low autofluorescence and high tissue transparency in the NIR region compared with other wavelength regions. However, existing NIR fluorescence probes for
Xianfeng Gu et al.
Journal of agricultural and food chemistry, 59(22), 11935-11939 (2011-10-18)
BODIPY-Le, a colorimetric and ratiometric fluorescent probe based on boron-dipyrromethene for selective detection sulfite ion, was investigated. Boron-dipyrromethene levulinyl ester (BODIPY-Le) is composed of an indole-based BODIPY dye and the levulinyl protective group, which could be easily and selectively deprotected
Kristiina Kanerva et al.
Developmental cell, 27(3), 249-262 (2013-11-12)
Mammalian cells acquire cholesterol, a major membrane constituent, via low-density lipoprotein (LDL) uptake. However, the mechanisms by which LDL cholesterol reaches the plasma membrane (PM) have remained obscure. Here, we applied LDL labeled with BODIPY cholesteryl linoleate to identify this
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