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Merck
CN

P1134

Porphobilinogen

powder

Synonym(s):

5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O4
CAS Number:
Molecular Weight:
226.23
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
207-666-3
Beilstein/REAXYS Number:
220051
MDL number:
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assay

≥96% (HPLC)

Quality Level

form

powder

solubility

1 M NH4OH: 10 mg/mL

storage temp.

−20°C

SMILES string

NCc1[nH]cc(CCC(O)=O)c1CC(O)=O

InChI

1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)

InChI key

QSHWIQZFGQKFMA-UHFFFAOYSA-N

Biochem/physiol Actions

Intermediate in the biosynthesis of heme.

Preparation Note

Enzymatically prepared.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Xinfu Zhang et al.
The Journal of organic chemistry, 77(1), 669-673 (2011-11-25)
In the orignial 1,3,5,7-tetraphenyl aza-BODIPY, replacing the phenyl rings with thiophene achieved significant bathochromic shifts. One of the target molecules, DPDTAB, emitting strong NIR fluorescence with a quantum yield of 0.46 in acetonitrile, is a very competitive NIR fluorophore.
Ton Schoenmaker et al.
Frontiers in endocrinology, 11, 501-501 (2020-08-08)
Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disease characterized by heterotopic ossification (HO) that occurs in muscle tissue, tendons, and ligaments. The disease is caused by mutations in the Activin receptor type I (ACVR1) gene resulting in enhanced responsiveness
Bingshuai Wang et al.
Chemical communications (Cambridge, England), 49(10), 1014-1016 (2012-12-22)
We have developed a new reversible fluorescence probe MPhSe-BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution and in living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that the probe has good cell



Global Trade Item Number

SKUGTIN
P1134-5MG04061834354048
P1134-1MG04061838357823
P1134-10MG04061834354031
P1134-50MG04061832402161