P1490
Pepsinogen I human
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About This Item
biological source
human
form
liquid
specific activity
≥500 U/mg (Lowry)
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... PGA3(643834), PGA4(643847), PGA5(5222), PGC(5225)
Biochem/physiol Actions
Studies show that smoking has an effect on the level of pepsinogen I present in serum in a H. pylori-dependent manner. Patients with lower titer levels had higher levels of pepsinogen I.
Used as a control in ELISA.
Physical form
0.2 μm filtered solution in Tris chloride, pH 8.5
Other Notes
One unit will produce a delta A280 of 0.001 per min at pH 2.0 at 37 deg C, measured as TCA-soluble products using hemoglobin as substrate. (Final Volume of reaction mixture = 16mL, 1 cm light path)
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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M Tatemichi et al.
Japanese journal of cancer research : Gann, 92(3), 243-248 (2001-03-27)
Serum pepsinogen (sPG) levels are used in gastric cancer screening programs. However, modification of sPG levels by smoking habit, according to the status of Helicobacter pylori (H. pylori) infection has been little investigated. This study investigated the effects of smoking