P204
Phenylbenzene ω-phosphono-α-amino acid
solid
Synonym(s):
3-[2′-Phosphonomethyl[1,1′-biphenyl]-3-yl]alanine, PMBA
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About This Item
Empirical Formula (Hill Notation):
C16H18NO5P
Molecular Weight:
335.29
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
solid
color
white
solubility
H2O: 0.15 mg/mL, DMSO: 0.2 mg/mL, 0.1 M NaOH: >10 mg/mL
SMILES string
N[C@@H](Cc1cccc(c1)-c2ccccc2CP(O)(O)=O)C(O)=O
InChI
1S/C16H18NO5P/c17-15(16(18)19)9-11-4-3-6-12(8-11)14-7-2-1-5-13(14)10-23(20,21)22/h1-8,15H,9-10,17H2,(H,18,19)(H2,20,21,22)/t15-/m0/s1
InChI key
NCEGJIHRQBRVJQ-HNNXBMFYSA-N
Gene Information
human ... GRIN1(2902)
Biochem/physiol Actions
Selective strychnine-sensitive glycine receptor antagonist.
Legal Information
Made and sold under license from Nippon Chemiphar.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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T Saitoh et al.
British journal of pharmacology, 113(1), 165-170 (1994-09-01)
1. 3-[2'-Phosphonomethyl[1,1'-biphenyl]-3-yl]alanine (PMBA) is a novel glycine antagonist at strychnine-sensitive receptors. The chemical structure of PMBA, possessing both a glycine moiety and a phosphono group, is quite different from that of strychnine. 2. In the spinal motoneurone of newborn rats
K Watanabe et al.
Soft matter, 14(17), 3372-3377 (2018-04-06)
An external electric AC field with a field strength ranging from 10 V mm-1 to 30 V mm-1 and a frequency ranging from 0.1 kHz to 1 MHz was applied to suspensions of gold nanoparticles (Au NPs) to control their
Kanako Watanabe et al.
Journal of colloid and interface science, 566, 202-210 (2020-02-02)
Assembly of plasmonic nanoparticle clusters having hotspots in a specific space is an effective way to efficiently utilize their plasmonic properties. In the assembly, however, bulk-like aggregates of the nanoparticles are readily formed by strong van der Waals forces, inducing