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Merck
CN

P2774

Pinane thromboxane A2

ethanol solution

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About This Item

Empirical Formula (Hill Notation):
C24H40O3
CAS Number:
Molecular Weight:
376.57
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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Product Name

Pinane thromboxane A2, ethanol solution

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1C[C@H]2C[C@@H]([C@@H]1C\C=C/CCCC(O)=O)C2(C)C

form

ethanol solution

shipped in

dry ice

storage temp.

−20°C

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R A Armstrong et al.
British journal of pharmacology, 84(3), 595-607 (1985-03-01)
The inhibitory effects of three prostanoid analogues, EP 045, EP 092 and pinane thromboxane A2 (PTA2), on the aggregation of human platelets in vitro have been investigated. In diluted platelet-rich plasma (PRP), EP 045 (20 microM) and EP 092 (1
B F Chumpitazi et al.
Clinical and experimental immunology, 111(2), 325-333 (1998-03-05)
The human platelet contribution against the intracellular growth of the parasite in vitro in human pulmonary fibroblasts was explored. It was observed that tachyzoites of Toxoplasma gondii induced activation of human platelets and additionally that platelets mediated inhibition of intracellular
J B Smith et al.
Prostaglandins, 33(6), 777-782 (1987-06-01)
Synthetic thromboxane A2 (TxA2S) induced rapid, concentration-dependent constriction of isolated perfused cat coronary arteries. Its potency was approximately 30 times that of the prostaglandin endoperoxide, PGH2. Pinane thromboxane A2 (PTA2), BM-13.505 and SQ-29,548, compounds previously shown to antagonize the effects
A M Lefer et al.
Prostaglandins and medicine, 3(3), 139-146 (1979-09-01)
Pinane thromboxane A2 (PTA2) an analog of thromboxane A2 that inhibits the formation of thromboxanes as well as antagonizes their biological actions, at an infusion rate of 1.0 mumole . kg-1 . h-1, prolonged survival in traumatic shock in rats.
Y Shibouta et al.
European journal of pharmacology, 85(1), 51-59 (1982-11-05)
In 6-week old spontaneously hypertensive rats (SHR), indomethacin (5 mg/kg i.v.) and pinane-thromboxane A2 (PTA2) (50 micrograms/kg per h i.v.) a thromboxane A2 (TXA2) antagonist as well as a TXA2 synthetase inhibitor, resulted in natriuresis accompanied by an increase in

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