P2774
Pinane thromboxane A2
ethanol solution
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About This Item
Empirical Formula (Hill Notation):
C24H40O3
CAS Number:
Molecular Weight:
376.57
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
ethanol solution
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCC[C@H](O)\C=C\[C@H]1C[C@H]2C[C@@H]([C@@H]1C\C=C/CCCC(O)=O)C2(C)C
Regulatory Information
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D M Roth et al.
Prostaglandins, leukotrienes, and medicine, 9(5), 503-509 (1982-11-01)
Six pinane-thromboxane A2 analogs have been synthesized and tested for their ability to antagonize carbocyclic thromboxane A2 (CTA2) induced coronary vasoconstriction and prostaglandin endoperoxide analog induced platelet aggregation. Two of the derivatives, 5C-15S BPTA2 and 5T-15S BPTA2 and 5T-15S BPTA2
P V Vrzheshch et al.
FEBS letters, 351(2), 168-170 (1994-09-05)
The phenomenon of supercooperativity in platelet aggregation is manifested by the occurrence of clear-cut thresholds in dose-response relationships; in such cases the Hill coefficient has unusually high values. Approximation, by the Hill equation, of the relationship of the rate of
Pinane thromboxane A2: a TXA2 antagonist with antithrombotic properties.
D Aharony et al.
Advances in prostaglandin and thromboxane research, 6, 489-492 (1980-01-01)