P2803
N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide
Synonym(s):
SC-9
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About This Item
Empirical Formula (Hill Notation):
C22H24ClNO2S
CAS Number:
Molecular Weight:
401.95
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
form
solid
storage temp.
−20°C
SMILES string
Clc1cccc2c(cccc12)S(=O)(=O)NCCCCCCc3ccccc3
InChI
1S/C22H24ClNO2S/c23-21-15-8-14-20-19(21)13-9-16-22(20)27(25,26)24-17-7-2-1-4-10-18-11-5-3-6-12-18/h3,5-6,8-9,11-16,24H,1-2,4,7,10,17H2
InChI key
YUXMTDYHFPRPLG-UHFFFAOYSA-N
Biochem/physiol Actions
Activates protein kinase C in a Ca2+-dependent manner
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P H Watson et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 7(6), 667-674 (1992-06-01)
The response of the parathyroid gland to low Ca2+ may be mediated in part by protein kinase C (PKC). We assessed the effect of two PKC activators, SC-9 and SC-10, and one PKC inhibitor, H-7, on Ca(2+)-regulated PTH release and
K Ashizawa et al.
Journal of reproduction and fertility, 101(3), 511-517 (1994-08-01)
The presence and possible role of protein kinase C in the regulation of fowl sperm functions were investigated. Immunoblot analysis of sperm extract using antibody to protein kinase C revealed a crossreacting protein of approximately 80 kDa. As the concentration
A D Blest et al.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 170(2), 189-199 (1992-02-01)
1. Retinae of crabs, Leptograpsus variegatus, held on a 12:12 h light-dark cycle were prepared for culture in vitro shortly before light-off. After an hour in darkness to permit the assembly of "night" rhabdoms, retinae were exposed to various combinations
R Yang et al.
Calcified tissue international, 61(1), 68-73 (1997-07-01)
Protein kinase C (PKC) plays an important role in the differentiation of cells, however, little is known about its relationship to bone metabolism. We have previously demonstrated that staurosporine concentration dependently transformed the cultured rat osteoblasts into stellate cells. In
M Kavaliers et al.
Brain research, 554(1-2), 65-71 (1991-07-19)
There is substantial evidence that magnetic fields can reduce opiate-induced analgesia, with alterations in calcium channel function and/or calcium ion flux being implicated in the mediation of these inhibitory effects. The present experiments were designed to examine the effects of
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