P2803
N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide
Synonym(s):
SC-9
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About This Item
Empirical Formula (Hill Notation):
C22H24ClNO2S
CAS Number:
Molecular Weight:
401.95
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
solid
InChI
1S/C22H24ClNO2S/c23-21-15-8-14-20-19(21)13-9-16-22(20)27(25,26)24-17-7-2-1-4-10-18-11-5-3-6-12-18/h3,5-6,8-9,11-16,24H,1-2,4,7,10,17H2
SMILES string
Clc1cccc2c(cccc12)S(=O)(=O)NCCCCCCc3ccccc3
InChI key
YUXMTDYHFPRPLG-UHFFFAOYSA-N
form
solid
storage temp.
−20°C
Biochem/physiol Actions
Activates protein kinase C in a Ca2+-dependent manner
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Kavaliers et al.
Brain research, 554(1-2), 65-71 (1991-07-19)
There is substantial evidence that magnetic fields can reduce opiate-induced analgesia, with alterations in calcium channel function and/or calcium ion flux being implicated in the mediation of these inhibitory effects. The present experiments were designed to examine the effects of
J Bargon et al.
The Journal of biological chemistry, 267(23), 16056-16060 (1992-08-15)
Epithelial cells utilize at least two types of apical Cl- channels, the cAMP-activated cystic fibrosis transmembrane conductance regulator (CFTR) and the Ca2+/calmodulin-dependent Cl- channel. While phorbal ester (PMA) activates only CFTR-dependent Cl- secretion and the Ca2+ ionophore A23187 only the
T Hirobe
Journal of cell science, 107 ( Pt 6), 1679-1686 (1994-06-01)
Mouse epidermal melanoblasts preferentially proliferated from disaggregated epidermal cell suspensions derived from newborn mouse skin in a serum-free melanoblast proliferation medium containing dibutyryl adenosine 3':5'-cyclic monophosphate and basic fibroblast growth factor. After 12 days, almost all of the keratinocytes died
B Petersen et al.
Cell biology and toxicology, 10(4), 219-230 (1994-08-01)
TGF-beta 1 is known as a potent inhibitor of proliferation of rat and human hepatocytes. In this study we show that the effects of TGF-beta 1 are quite different on mouse hepatocytes. In rat and human hepatocytes, TGF-beta 1 inhibited
K Ashizawa et al.
Journal of reproduction and fertility, 101(3), 511-517 (1994-08-01)
The presence and possible role of protein kinase C in the regulation of fowl sperm functions were investigated. Immunoblot analysis of sperm extract using antibody to protein kinase C revealed a crossreacting protein of approximately 80 kDa. As the concentration
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