P3168
Phytic acid dodecasodium salt hydrate
≥90%, from rice
Synonym(s):
myo-Inositol hexakis(dihydrogen phosphate), Inositol hexakisphosphate, Inositol hexaphosphoric acid, InsP6
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About This Item
Empirical Formula (Hill Notation):
C6H6Na12O24P6 · xH2O
CAS Number:
Molecular Weight:
923.82 (anhydrous basis)
UNSPSC Code:
12352201
MDL number:
SMILES string
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H]O[H].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O
biological source
rice
assay
≥90%
Biochem/physiol Actions
Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).
Analysis Note
Contains minute amounts of black particles.
Regulatory Information
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Andreia Biolo et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1926-1929 (2009-02-11)
A major determinant of maximal exercise capacity is the delivery of oxygen to exercising muscles. myo-Inositol trispyrophosphate (ITPP) is a recently identified membrane-permeant molecule that causes allosteric regulation of Hb oxygen binding affinity. In normal mice, i.p. administration of ITPP
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