P3683
Paraplast Plus®
for tissue embedding
Synonym(s):
Paraplast Plus® embedding media, Paraffin – polyisobutylene mixture
Quality Level
form
solid
mp
56-57 °C (lit.)
56-57 °C
application(s)
hematology
histology
storage temp.
room temp
General description
Paraplast Plus® is a refined mixture of highly purified paraffin containing complex elastomer of regulated molecular weights plus a small percentage of dimethyl sulfoxide (DMSO) for fast tissue penetration. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.
Application
Paraplast Plus® is recommended for large specimens and tissue that commonly presents infiltration problems. It has been used:
- in the examination of vertebral specimens of Malacoraja senta.
- in the identification and expression analysis of PIN genes in rice.
- in the study of glucose transport mechanisms in uterine tissues during pregnancy.
- to embed Bouin′s fixed carp tissues, rat ventral prostatic fragments, and common bean (Phaseolus vulgaris L.) nodules.
Features and Benefits
- Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
- 0.8% DMSO enhances ease of infiltration and sectioning for tissues difficult to process with regular Paraplast.
- Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
- Optimal infiltration and embedding for high-quality sections.
- Great compression resistance and ribbon continuity.
- Remarkable morphology preservation and distortion-free sections.
Legal Information
Paraplast is a registered trademark of Leica Biosystems
Paraplast Plus is a registered trademark of Leica Biosystems
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Micro-morphology of common bean (Phaseolus vulgaris L.)
nodules undergoing senescence
nodules undergoing senescence
Fabia'n Ferna'ndez-Luquen?o ? L.
Acta Physiologiae Plantarum / Polish Academy of Sciences, Committee of Plant Physiology Genetics and Breeding (2008)
Nozomu Yoshioka et al.
Disease models & mechanisms, 13(5) (2020-06-03)
Loss-of-function mutations in dystonin (DST) can cause hereditary sensory and autonomic neuropathy type 6 (HSAN-VI) or epidermolysis bullosa simplex (EBS). Recently, DST-related diseases were recognized to be more complex than previously thought because a patient exhibited both neurological and skin
Identification and expression analysis of PIN genes in rice
Miyashita, et al.
Plant Science, 178(5) (2010)
Shuaibin Zhang et al.
Scientific reports, 6, 23173-23173 (2016-03-19)
Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied
Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Yugantak Raj Gupta
Aquaculture International (2017)
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