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P3761

Pentobarbital sodium salt

Name: Pentobarbital sodium salt
Brand: SIGMA

Synonym(s):

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₇N₂NaO₃

CAS Number:

57-33-0

Molecular Weight:

248.25

UNSPSC Code:

41116107

PubChem Substance ID:

24898448

EC Number:

200-323-9

MDL number:

MFCD00070198

Form:

powder

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Properties

form

powder

Quality Segment

200

drug control

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

solubility

H₂O: soluble, alcohol: soluble

SMILES string

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;

InChI key

PGOYUXGHADTNIB-UHFFFAOYSA-N

Description

Application

Pentobarbital sodium salt has been used as an anesthetic in rats and mice prior to various in vitro studies.

Biochem/physiol Actions

Pentobarbital (PB) is a barbiturate and a ligand of the γ-aminobutyric acid subtype A (GABAA) receptor. It is a sedative anesthetic majorly used in rodent euthanasia. Pentobarbital possesses hypnotic functionality and muscle relaxing properties. It enhances GABAergic activity. Intraperitoneal injection of PB may result in loss of righting reflex (LORR) and heartbeat cessation.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301,H336,H361d

pcodes

P202 - P261 - P264 - P271 - P280 - P301 + P310

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c