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Merck
CN

P3886

Sigma-Aldrich

Poly-L-proline

suitable for ligand binding assays, Mol wt >30,000

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About This Item

Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
25191-13-3
Molecular Weight:
115.13
MDL number:
MFCD00166364
UNSPSC Code:
12352209
PubChem Substance ID:
24898465
NACRES:
NA.26

Key Documents

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Product Name

Poly-L-proline, mol wt >30,000

form

powder

mol wt

>30,000

technique(s)

ligand binding assay: suitable

color

white to light yellow

storage temp.

−20°C

SMILES string

OC(=O)C1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)

InChI key

ONIBWKKTOPOVIA-UHFFFAOYSA-N

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Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
057K5107
020K5902
041H5503
041H5501
126H5516

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Helena Bysell et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 522-528 (2008-12-09)
The relative importance of electrostatic and nonelectrostatic interactions in peptide-microgel systems was evaluated by micromanipulator-assisted light microscopy, confocal microscopy, and circular dichroism. For this purpose, the interaction of various homopolypeptides with lightly cross-linked polyelectrolyte gel particles ( approximately 70 microm
Susanne Ude et al.
Science (New York, N.Y.), 339(6115), 82-85 (2012-12-15)
Translation elongation factor P (EF-P) is critical for virulence in bacteria. EF-P is present in all bacteria and orthologous to archaeal and eukaryotic initiation factor 5A, yet the biological function has so far remained enigmatic. Here, we demonstrate that EF-P
Manuel E Patarroyo et al.
Biochemical and biophysical research communications, 429(1-2), 75-80 (2012-11-13)
Modified HABP (mHABP) regions interacting with HLA-DRβ1(∗) molecules have a more restricted conformation and/or sequence than other mHABPs which do not fit perfectly into their peptide binding regions (PBR) and do not induce an acceptable immune response due to the
Alexei A Adzhubei et al.
Journal of molecular biology, 425(12), 2100-2132 (2013-03-20)
The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the folded and unfolded proteins. Although much less abundant
Conor C G Scully et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(49), 15612-15617 (2012-11-06)
Bent but not broken: cyclic oligoprolines are accessed in a reaction that effectively bends rigid oligoproline peptides (see scheme; TBDMS=tert-butyldimethylsilyl). The stitching is accomplished during macrocyclization enabled by aziridine aldehydes and isocyanides. Molecular modeling studies suggest that electrostatic attraction between
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