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Merck
CN

P4120

Pioglitazone hydrochloride

≥99% (HPLC)

Synonym(s):

Pioglitazone HCl, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H20N2O3S · HCl
CAS Number:
112529-15-4
Molecular Weight:
392.90
UNSPSC Code:
12352200
MDL number:
MFCD04975446

Key Documents

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InChI key

GHUUBYQTCDQWRA-UHFFFAOYSA-N

InChI

1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H

SMILES string

Cl.CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1

assay

≥99% (HPLC)

color

white

solubility

DMSO: soluble 27 mg/mL, H2O: insoluble

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Biochem/physiol Actions

Pioglitazone hydrochloride is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic.
Pioglitazone hydrochloride is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
045K0849
124K1330
094K0901
053K4705
074K0644

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