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Merck
CN

P4631

Sigma-Aldrich

Phosphodiesterase I from Bothrops atrox

Type V, crude dried venom, ≥0.01 unit/mg solid

Synonym(s):

5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase

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About This Item

EC Number:
EC Number:
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.32
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type

Type V

form

crude dried venom

specific activity

≥0.01 unit/mg solid

storage temp.

−20°C

Other Notes

One unit will hydrolyze 1.0 μmole of bis(p-nitrophenyl) phosphate per min at pH 8.8 at 37 °C.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Leonie F A Huitema et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(52), 21372-21377 (2012-12-14)
Bone mineralization is an essential step during the embryonic development of vertebrates, and bone serves vital functions in human physiology. To systematically identify unique gene functions essential for osteogenesis, we performed a forward genetic screen in zebrafish and isolated a
Jonathan M Flanagan et al.
Blood, 121(16), 3237-3245 (2013-02-21)
Stroke is a devastating complication of sickle cell anemia (SCA), occurring in 11% of patients before age 20 years. Previous studies of sibling pairs have demonstrated a genetic component to the development of cerebrovascular disease in SCA, but few candidate
Aurora Mejía-Benítez et al.
BMC medical genetics, 14, 21-21 (2013-02-05)
Recent genome wide association studies (GWAS) and previous positional linkage studies have identified more than 50 single nucleotide polymorphisms (SNPs) associated with obesity, mostly in Europeans. We aimed to assess the contribution of some of these SNPs to obesity risk
Antonella Marucci et al.
Biochimica et biophysica acta, 1833(6), 1388-1395 (2013-03-19)
Ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin signaling and action. Understanding the mechanisms underlying ENPP1 expression may help unravel molecular mechanisms of insulin resistance. Recent data suggest a role of ENPP1-3'untraslated region (UTR), in controlling ENPP1 expression. We sought to
Qiaoli Li et al.
Disease models & mechanisms, 6(5), 1227-1235 (2013-06-27)
Generalized arterial calcification of infancy (GACI), an autosomal recessive disorder, is characterized by early mineralization of blood vessels, often diagnosed by prenatal ultrasound and usually resulting in demise during the first year of life. It is caused in most cases

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