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Merck
CN

P4635

Phosphocreatine di(tris) salt

~98%

Synonym(s):

Creatine phosphate di(tris) salt, N-(Imino[phosphonoamino]methyl)-N-methylglycine

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About This Item

Empirical Formula (Hill Notation):
C4H10N3O5P · 2C4H11NO3
CAS Number:
108321-17-1
Molecular Weight:
453.38
UNSPSC Code:
12352200
PubChem Substance ID:
329820211
MDL number:
MFCD00069590

Key Documents

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InChI

1S/C4H10N3O5P.2C4H11NO3/c1-7(2-3(8)9)4(5)6-13(10,11)12;2*5-4(1-6,2-7)3-8/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);2*6-8H,1-3,5H2

SMILES string

NC(CO)(CO)CO.NC(CO)(CO)CO.CN(CC(O)=O)C(=N)NP(O)(O)=O

InChI key

UPPBKCOGWJTQMJ-UHFFFAOYSA-N

assay

~98%

storage temp.

−20°C

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Application

For use in systems where alkali metal ions are undesirable.

Biochem/physiol Actions

High-energy phosphate reservoir in vertebrate and some invertebrate muscle; provides phosphate for ADP-ATP conversion
High-energy phosphate reservoir in vertebrate and some invertebrate muscle; provides phosphate for ADP-ATP conversion. As a non-oxidative reservoir of high-energy phosphate, phosphocreatine protects against anoxic and ischemic damage to brain neurons.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
064H5772
036H5731
036H5730

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Sofía Muñoz et al.
Molecular cell, 74(4), 664-673 (2019-03-30)
Cohesin is a conserved, ring-shaped protein complex that topologically embraces DNA. Its central role in genome organization includes functions in sister chromatid cohesion, DNA repair, and transcriptional regulation. Cohesin loading onto chromosomes requires the Scc2-Scc4 cohesin loader, whose presence on
Lou Beaulieu-Laroche et al.
Neuron, 103(2), 235-241 (2019-06-11)
Dendritic integration can expand the information-processing capabilities of neurons. However, the recruitment of active dendritic processing in vivo and its relationship to somatic activity remain poorly understood. Here, we use two-photon GCaMP6f imaging to simultaneously monitor dendritic and somatic compartments in

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