P4747
Anti-Potassium Channel KCa2.3, (C-term) (Small-conductance Ca2+-activated Potassium Channel 3) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-SK3, Anti-SKCa3
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, mouse, rat, pig
technique(s)
western blot: 1:200 using rat brain membranes
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KCNN3(3782)
mouse ... Kcnn3(140493)
rat ... Kcnn3(54263)
Immunogen
Synthetic peptide corresponding to amino acid residues 659-674 of human KCa2.3. This sequence has 100% homology in rat, mouse, pig.
Physical form
Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Sang-Gyun Kang et al.
Cells, 12(14) (2023-07-29)
Prion diseases are progressive neurodegenerative disorders affecting humans and various mammals. The prominent neuropathological change in prion-affected brains is neuroinflammation, histopathologically characterized by reactive gliosis surrounding prion deposition. The cause and effect of these cellular responses are still unclear. Here
Shaun L Sandow et al.
Journal of anatomy, 209(5), 689-698 (2006-10-26)
Activation of endothelial cell small- (S) and intermediate- (I) conductance calcium-activated potassium channels (K(Ca)) and current or molecular transfer via myoendothelial gap junctions underlies endothelium-derived hyperpolarization leading to vasodilation. The mechanism underlying the K(Ca) component of vasodilator activity and the
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