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P4807

Penicillin V potassium salt

powder, BioReagent, suitable for cell culture

Synonym(s):

Phenoxymethylpenicillinic acid potassium salt, Penicillin V potassium salt

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About This Item

Empirical Formula (Hill Notation):
C16H17N2O5SK
Molecular Weight:
388.48
UNSPSC Code:
51101500
PubChem Substance ID:
24898501
EC Number:
205-086-5
MDL number:
MFCD00051771
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product line

BioReagent

form

powder

specific activity

~1,500 U/mg

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 400 mg, clear, colorless to faintly yellow (Solvent: 400 mL plus 4 mL of H2O)

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

SMILES string

[K+].CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C16H18N2O5S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

HCTVWSOKIJULET-LQDWTQKMSA-M

General description

Chemical structure: β-lactam

Biochem/physiol Actions

Penicillin V inhibits the synthesis of bacterial cell walls by blocking cell wall peptidoglycan chain cross-linking. Used in cell culture in combination with streptomcyin and other antibiotics.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
100M0801
060M0794
088K10461
016K04821
016K0482

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Adel Ben Salem et al.
Bioorganic & medicinal chemistry, 19(24), 7534-7540 (2011-11-15)
Two well-known antibiotic heterocycles, the 'quinolone' nalidixic acid and the β-lactam penicillin V, active at different levels of the bacterial growth process, have been attached via an ether-ester junction to the p-tert-butylcalix[4]arene lower rim, in alternate position. The resulting hydrophobic