P5523
Phe-Leu-Glu-Glu-Leu
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C31H47N5O10
CAS Number:
Molecular Weight:
649.73
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
assay
≥97% (HPLC)
form
powder
storage temp.
−20°C
SMILES string
CC(C)CC(NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(N)Cc1ccccc1)C(O)=O
InChI
1S/C31H47N5O10/c1-17(2)14-23(35-27(41)20(32)16-19-8-6-5-7-9-19)30(44)34-21(10-12-25(37)38)28(42)33-22(11-13-26(39)40)29(43)36-24(31(45)46)15-18(3)4/h5-9,17-18,20-24H,10-16,32H2,1-4H3,(H,33,42)(H,34,44)(H,35,41)(H,36,43)(H,37,38)(H,39,40)(H,45,46)
InChI key
JNBCIUTTWUUDDX-UHFFFAOYSA-N
General description
Substrate for vitamin K-dependent carboxylation studies.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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D H Rich et al.
International journal of peptide and protein research, 18(1), 41-51 (1981-07-01)
The synthesis of two analogs of sequence 18-23 of bovine prothrombin precursor is described. Hexapeptides Boc-Cys (Acm)-Leu-Glu(OBzl)-Glu(OBzl)-Pro-Cys (Acm)-OBzl and Ac-Cys(Acm-Leu-Glu(OBzl)-Glu(OBzl)-Pro-Cys(Acm)-OMe were synthesized in solution by stepwise addition of Boc-amino acids using dicyclohexylcarbodiimide/N-hydroxybenzotriazole as the coupling reagent. The acetamidomethyl groups were
D H Rich et al.
FEBS letters, 152(1), 79-82 (1983-02-07)
Liver microsomes contain a vitamin K and O2-dependent carboxylase that converts peptide-bound glutamyl residues to gamma-carboxyglutamate residues. The peptide Boc-O-phospho-Ser-O-phospho-Ser-Leu-OMe has now been synthesized. This peptide inhibits the carboxylation of endogenous protein precursors by a detergent-solubilized preparation of the carboxylase
Synthesis of two analogs of a cyclic hexapeptide with disulfide bridge corresponding to bovine prothrombin precursor sequence 18-23. Extent of carboxylation by Vitamin K-Dependent carboxylase.
Rich DH, Kawai M, Goodman HL, Suttie JW.
International Journal of Peptide and Protein Research, 18, 41-51 (1081)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5523-100MG | 04061831590357 |