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Merck
CN

P5990

Sigma-Aldrich

Protein kinase A inhibitor fragment 14-24 trifluoroacetate salt

≥90% (HPLC), lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
41106305
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Assay

≥90% (HPLC)

form

lyophilized powder

mol wt

calculated mol wt 1250

composition

Protein Content, ≥55%

solubility

H2O: soluble

storage temp.

−20°C

SMILES string

OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(N)=O

Amino Acid Sequence

Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-NH2

Biochem/physiol Actions

cAMP-dependent protein kinase inhibitor.

Other Notes

cAMP-dependent protein kinase inhibitor

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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W Nörenberg et al.
Amino acids, 14(1-3), 33-39 (1999-01-01)
Whole-cell patch clamp experiments were carried out in rat striatal brain slices. In a subset of striatal neurons (70-80%), NMDA-induced inward currents were inhibited by the adenosine A2A receptor selective agonist CGS 21680. The non-selective adenosine receptor antagonist 8-(p-sulphophenyl)-theophylline and

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