P6135
Phospholipase C from Bacillus cereus
Type III, lyophilized powder, 100-200 units/mg protein (using soybean L-α-phosphatidylcholine)
Synonym(s):
Lecithinase C, Lipophosphodiesterase I, PC-PLC, Phosphatidylcholine cholinephosphohydrolase
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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-638-2
MDL number:
type
Type III
form
lyophilized powder
specific activity
100-200 units/mg protein (using soybean L-α-phosphatidylcholine)
composition
Protein, ~10% Lowry
storage temp.
−20°C
Gene Information
Bacillus cereus ATCC 10987 ... plC(2749087)
Biochem/physiol Actions
Hydrolyzes the phosphate bond on phosphatidylcholine and other glycerophospholipids yielding diacylglycerol; this enzyme will also hydrolyze the phosphate bonds of sphingomyelin, cardiolipin, choline plasmalogen and ceramide phospholipids.
Physical form
Contains Tris buffer salts and ZnSO4
Other Notes
One unit will liberate 1.0 μmole of water soluble organic phosphorus from L-α-phosphatidylcholine per min at pH 7.3 at 37 °C.
Regulatory Information
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Shigeki Nakamura et al.
PLoS pathogens, 7(1), e1001247-e1001247 (2011-01-22)
Non-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing isolates from the upper airway, LRT isolates, especially those associated
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