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Merck
CN

P6517

Sigma-Aldrich

1,2-Distearoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):

PC, 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin, DSPC, PC(18:0/18:0)

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About This Item

Empirical Formula (Hill Notation):
C44H88NO8P
CAS Number:
Molecular Weight:
790.15
Beilstein:
3923978
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
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Assay

≥99% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

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General description

Non-pyrogenic, well-defined liposomes, loaded with a molecule of choice, are formed by a single hydration step.

Preparation Note

A further purification by crystallization of P1138.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Corrigendum to "Non-linear Response and Viscoelastic Properties of Lipid-Coated Microbubbles: DSPC versus DPPC" (Ultrasound Med Biol 2015;41:1432-1445).
Tom van Rooij et al.
Ultrasound in medicine & biology, 47(6), 1640-1640 (2021-03-19)
Corrigendum to "In Vivo Characterization of Ultrasound Contrast Agents: Microbubble Spectroscopy in a Chicken Embryo" (Ultrasound Med Biol 2012;38:1608-1617).
Telli Faez et al.
Ultrasound in medicine & biology, 47(6), 1638-1638 (2021-03-19)
Corrigendum to "Secondary Bjerknes Forces Deform Targeted Microbubbles" (Ultrasound Med Biol 2013;39:490-506).
Tom J A Kokhuis et al.
Ultrasound in medicine & biology, 47(6), 1639-1639 (2021-03-19)
Ilya Skachkov et al.
PloS one, 13(9), e0204354-e0204354 (2018-09-21)
In vivo cell tracking of therapeutic, tumor, and endothelial cells is an emerging field and a promising technique for imaging cardiovascular disease and cancer development. Site-specific labeling of endothelial cells with the MRI contrast agent superparamagnetic iron oxide (SPIO) in
Mette Marie Bruun Nielsen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(5), 1525-1532 (2013-01-04)
Imaging ellipsometry (IE) has been applied to generate laterally resolved thickness maps of spin-coated membranes in both the dry and fully hydrated state. Spin-coating offers a convenient preparation method for stacked supported membranes, and in-depth thickness maps for such films

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