P6610
Anti-Potassium Channel Kir4.1 antibody produced in rabbit
affinity isolated antibody, lyophilized powder
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About This Item
MDL number:
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
form
lyophilized powder
species reactivity
rat
technique(s)
western blot (chemiluminescent): suitable
storage temp.
−20°C
Gene Information
human ... KCNJ10(3766)
mouse ... Kcnj10(16513)
rat ... Kcnj10(29718)
Immunogen
Purified peptide antigen corresponding to residues 356-375 of rat, mouse, or human Kir4.1.
Physical form
Lyophilized at ~0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.
Regulatory Information
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Ge Tan et al.
Biochemical and biophysical research communications, 367(4), 743-747 (2008-01-15)
Inward rectifying potassium channels (Kir), and in particular Kir 4.1, are key regulators of glial functions, which in turn determine neuronal excitability and axonal conduction. A high expression of Kir 4.1 has been detected in in some pathological conditions. In
P Kofuji et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(15), 5733-5740 (2000-07-26)
The inwardly rectifying potassium channel Kir4.1 has been suggested to underlie the principal K(+) conductance of mammalian Müller cells and to participate in the generation of field potentials and regulation of extracellular K(+) in the retina. To further assess the
W L Pearson et al.
The Journal of physiology, 514 ( Pt 3), 639-653 (1999-01-12)
1. A low stringency polymerase chain reaction (PCR) homology screening procedure was used to probe a mouse liver cDNA library to identify novel inward rectifier K+ channel genes. A single gene (mLV1) was identified that exhibited extensive sequence homology with
Jiangang Gao et al.
Molecular and cellular biology, 27(12), 4500-4512 (2007-04-18)
The function of the orphan glutamate receptor delta subunits (GluRdelta1 and GluRdelta2) remains unclear. GluRdelta2 is expressed exclusively in the Purkinje cells of the cerebellum, and GluRdelta1 is prominently expressed in inner ear hair cells and neurons of the hippocampus.
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