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Merck
CN

P6785

Phe-Met-Arg-D-Phe amide

≥97% (HPLC)

Synonym(s):

[D-Phe4]-Molluscan cardioexcitatory neuropeptide

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About This Item

Empirical Formula (Hill Notation):
C29H42N8O4S
CAS Number:
Molecular Weight:
598.76
UNSPSC Code:
12352200
PubChem Substance ID:
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InChI

1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)

InChI key

WCSPDMCSKYUFBX-UHFFFAOYSA-N

assay

≥97% (HPLC)

composition

Peptide content, ~65%

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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V Dyachuk et al.
Acta biologica Hungarica, 63 Suppl 2, 221-229 (2012-08-30)
Bivalve larvae use catch muscles for rapid shell closure and maintenance of the closed condition. We used specific antibodies against the muscle proteins together with phalloidin and neuronal markers, FMRFamide and serotonin (5-HT), to analyze mutual distribution of muscle and
Chris Li et al.
Learning & memory (Cold Spring Harbor, N.Y.), 20(2), 103-108 (2013-01-18)
Lasting memories are likely to result from a lasting change in neurotransmission. In the nematode Caenorhabditis elegans, spaced training with a tap stimulus induces habituation to the tap that lasts for >24 h and is dependent on glutamate transmission, postsynaptic
Modi Roopin et al.
Journal of pineal research, 53(3), 259-269 (2012-04-18)
While recent advances suggest functional pleiotropy of melatonin in higher organisms, an understanding of the biological significance of this ancient molecule in early evolutionary groups is lacking. Here, endogenous melatonin production was identified for the first time in the sea
Tamara M Stawicki et al.
PLoS genetics, 9(5), e1003472-e1003472 (2013-05-10)
Neuropeptides play crucial roles in modulating neuronal networks, including changing intrinsic properties of neurons and synaptic efficacy. We previously reported a Caenorhabditis elegans mutant, acr-2(gf), that displays spontaneous convulsions as the result of a gain-of-function mutation in a neuronal nicotinic
Natalia Kreshchenko et al.
Acta biologica Hungarica, 63 Suppl 2, 83-87 (2012-08-30)
The details of the morphology of the nervous system has been investigated in two turbellarian species Polycelis tenuis and Girardia tigrina using confocal laser scanning microscopy and immunostaining to neuropeptide FMRFamide. Abundant FMRFamide immunoreactivity (FMRF-IR) has been observed in central

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