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Merck
CN

P6902

Pheniramine maleate salt

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About This Item

Empirical Formula (Hill Notation):
C16H20N2 · C4H4O4
CAS Number:
Molecular Weight:
356.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
205-051-4
MDL number:
Form:
powder
Quality level:
Technical Service
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InChI key

SSOXZAQUVINQSA-BTJKTKAUSA-N

InChI

1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES string

OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccccc1)c2ccccn2

form

powder

Quality Level

Gene Information

human ... HRH1(3269)

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Biochem/physiol Actions

Pheniramine maleate is a H1 histamine receptor antagonist. It is an alkylamine derivative. Structurally, pheniramine contains a chiral carbon atom with a hydrogen atom. Other substituents include the pyridyl, alkylamine and phenyl groups. It is used as an antiallergic drug for treating the common cold, respiratory allergies, urticaria, and systematic allergic reactions.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3


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Wenhua Gao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 904, 121-127 (2012-08-21)
A rapid and efficient dual preconcentration method of on-line single drop liquid-liquid-liquid microextraction (SD-LLLME) coupled to sweeping micellar electrokinetic chromatography (MEKC) was developed for trace analysis of three antihistamines (mizolastine, chlorpheniramine and pheniramine) in human urine. Three analytes were firstly
Kerem Karaman et al.
American journal of surgery, 205(2), 213-219 (2012-09-05)
Laparoscopic cholecystectomy (LC) still leads to significant postoperative nausea and vomiting (PONV) and pain. Our aim was to evaluate the efficacy of dexamethasone or pheniramine hydrogen maleate, either alone or combined, in reducing the stress response and symptoms after LC.
Ana B Guimaraes-Correa et al.
Viruses, 3(7), 1041-1058 (2011-10-14)
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that occurs in individuals infected with the human T lymphotropic virus type 1 (HTLV-1). Patients with aggressive ATLL have a poor prognosis because the leukemic cells are resistant to conventional chemotherapy.
M R Louhaichi et al.
Talanta, 78(3), 991-997 (2009-03-10)
A new simple, rapid and sensitive liquid chromatographic method has been developed and validated for the simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold pharmaceuticals. The separation of these compounds was achieved within 13
Ho Jun Lee et al.
Journal of Korean medical science, 24(5), 879-882 (2009-10-02)
The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in

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