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Merck
CN

P7081

1,2-Didecanoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):

PC, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt, 1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, L-α-Phosphatidylcholine, didecanoyl, Didecanoyllecithin, PC(10:0/10:0)

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About This Item

Empirical Formula (Hill Notation):
C28H56NO8P
CAS Number:
3436-44-0
Molecular Weight:
565.72
PubChem Substance ID:
24898817
UNSPSC Code:
51191904
Beilstein/REAXYS Number:
3757665
MDL number:
MFCD00063538

Key Documents

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Product Name

1,2-Didecanoyl-sn-glycero-3-phosphocholine, ≥99% (TLC)

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O

InChI key

MLKLDGSYMHFAOC-AREMUKBSSA-N

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1

assay

≥99% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Quality Level

200

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
120M5222V
120M5222
029K5206
064K5210
055H8377

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Studies on the complex formed between glucagon and dicaprylphosphatidylcholine.
J R Ernandes et al.
Biochimica et biophysica acta, 733(1), 75-86 (1983-08-24)
S Carstens et al.
Diabetes, 42(7), 1032-1040 (1993-07-01)
To investigate the short-term effects of didecanoyl-L-alpha-phosphatidylcholine on the nasal mucosa and the mechanism by which didecanoyl-L-alpha-phosphatidylcholine enhances the nasal absorption of insulin, an in vitro model was developed. The mucosa from the posterior part of the rabbit nasal septum
M A Unmack et al.
Pflugers Archiv : European journal of physiology, 434(3), 234-241 (1997-07-01)
The effects of mucosal application of the short-chain phospholipid didecanoyl-L-alpha-phosphatidylcholine (DDPC; with two saturated 10-carbon acyl chains) on active Na+ transport and transepithelial conductance (G) in the frog skin (Rana temporaria) were investigated. Active Na+ transport was measured as the
T Laursen et al.
The Annals of pharmacotherapy, 28(7-8), 845-848 (1994-07-01)
Current growth hormone (GH) therapy with daily subcutaneous injections results in elevated serum concentrations of GH lasting for several hours, whereas physiologic GH secretion is characterized by a short-duration peak and low basal concentrations. A closer imitation of this pattern
Cécile Loudet et al.
Biochimica et biophysica acta, 1724(3), 315-323 (2005-06-18)
Mixtures of dicaproyl- (DC), dimyristoyl- (DM) and 1-tetradecanoyl-2-biphenylbutanoyl-(TBB) phosphatidylcholine (PC) in water produce bicelle membranes that are oriented by magnetic fields. DMPC/DCPC systems orient such that their membrane plane is parallel to the magnetic field, whereas for TBBPC/DCPC, the plane
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