P7209
1-Pyrenedodecanoic acid
≥90% (TLC)
Synonym(s):
12-(1-Pyrenyl)dodecanoic acid
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About This Item
Empirical Formula (Hill Notation):
C28H32O2
CAS Number:
Molecular Weight:
400.55
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
2481235
MDL number:
InChI key
JORFLUCVQONOPN-UHFFFAOYSA-N
SMILES string
OC(=O)CCCCCCCCCCCc1ccc2ccc3cccc4ccc1c2c34
InChI
1S/C28H32O2/c29-26(30)14-9-7-5-3-1-2-4-6-8-11-21-15-16-24-18-17-22-12-10-13-23-19-20-25(21)28(24)27(22)23/h10,12-13,15-20H,1-9,11,14H2,(H,29,30)
assay
≥90% (TLC)
storage temp.
2-8°C
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Analysis Note
Probe for studying uptake into cultured cells by FCM
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F Ojima et al.
Free radical biology & medicine, 15(4), 377-384 (1993-10-01)
Human plasma and plasma low-density lipoprotein (LDL) were exposed to photoirradiation in the presence of methylene blue (water-soluble photosensitizer) or 12-(1-pyrene)dodecanoic acid (P-12, lipid-soluble photosensitizer). In methylene-blue-sensitized photooxidation of human plasma and LDL, endogenous carotenoids and tocopherols were consumed with
E Fibach et al.
Cytometry, 9(6), 525-528 (1988-11-01)
The fluorescence activated cell sorter (FACS) was used for measuring the uptake of the fluorescent fatty acid derivative 12-(1-pyrene) dodecanoic acid (P12) by human peripheral blood cells. The results indicate that blood cells differ widely in their ability to take
E Spisni et al.
Biochimica et biophysica acta, 1402(1), 61-69 (1998-04-29)
Zellweger fibroblasts, which are devoid of peroxisomes and fail to synthesize plasmalogens, are very sensitive to the killing effect triggered by UV-activated 12-(1-pyrene) dodecanoic acid (P12). Although in some studied performed, it is assumed that reactive oxygen species (ROS) may
K Okumoto et al.
Experimental cell research, 233(1), 11-20 (1997-05-25)
We made use of the 9-(1'-pyrene)nonanol/ultraviolet (P9OH/UV) method and isolated peroxisome-deficient mutant cells. TKa cells, the wild-type Chinese hamster ovary (CHO) cells, CHO-K1, that had been stably transfected with cDNA encoding Pex2p (formerly peroxisome assembly factor-1, PAF-1) were used to
S Gatt et al.
Biochimica et biophysica acta, 943(3), 447-453 (1988-09-01)
Pyrene dodecanoic acid (P12), a medium-chain fatty acid to which the fluorescent probe pyrene is covalently linked, showed a considerable increase in fluorescence when the probe was introduced into a hydrophobic environment. Also, when closely packed in an aggregate, an
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