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Merck
CN

P7383

Sigma-Aldrich

Pyrophosphatase, Nucleotide from Crotalus adamanteus venom

Type II, lyophilized powder, 4-8 units/mg protein, vial of ~25 units

Synonym(s):

Dinucleotide nucleotidohydrolase

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
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type

Type II

form

lyophilized powder

specific activity

4-8 units/mg protein

packaging

vial of ~25 units

foreign activity

5′-nucleotidase <0.003 units/mg protein
alkaline phosphatase <0.002 units/mg protein
phosphodiesterase 0.2 - 0.4 units/mg protein

storage temp.

−20°C

Physical form

Lyophilized powder containing approx. 35% Tris buffer salts.

Other Notes

One unit will hydrolyze 1.0 μmole of β-NAD to NMN and AMP per min at pH 7.4 at 37 °C in the presence of Mg ions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Shunji Matsunaga
Clinical calcium, 19(10), 1415-1420 (2009-10-02)
The study aimed for epidemiology and pathogenesis of ossification of the posterior longitudinal ligament of the cervical spine (OPLL) has been continued by The Investigation Committee of Japanese Ministry of Health, Labour and Welfare till now. As a result, the
Gennady G Yegutkin et al.
The Journal of physiology, 579(Pt 2), 553-564 (2007-01-06)
Extracellular ATP and ADP trigger vasodilatatory and prothrombotic signalling events in the vasculature. Here, we tested the hypothesis that nucleotide turnover is activated in the bloodstream of exercising humans thus contributing to the enhanced platelet reactivity and haemostasis. Right atrial
Iris J Joye et al.
Applied microbiology and biotechnology, 90(1), 173-180 (2010-12-31)
Nucleotide pyrophosphatases/phosphodiesterases (NPPs, PF01663) release nucleoside 5'-monophosphates from a wide range of nucleotide substrates. Only very recently, the first plant members of the NPP family were characterised (Joye et al. J Cereal Sci 51: 326-336, 2010), and little is known
Jesse G Zalatan et al.
Journal of molecular biology, 384(5), 1174-1189 (2008-10-15)
Mechanistic models for biochemical systems are frequently proposed from structural data. Site-directed mutagenesis can be used to test the importance of proposed functional sites, but these data do not necessarily indicate how these sites contribute to function. In this study
Zhongqi He et al.
Bioresource technology, 97(14), 1660-1668 (2005-09-13)
Characterizing labile P forms in animal manure is a challenge due to their susceptibility to hydrolysis. In this study, we enzymatically characterized P forms in dairy manure (no bedding), collected from a representative dairy farm in New York, by separating

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