P7637
Poly-L-arginine sulfate salt
mol wt 15,000-50,000
SMILES string
OS(O)(=O)=O.NC(CCCNC(N)=N)C(O)=O
mol wt
15,000-50,000
storage temp.
−20°C
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Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Other Notes
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Gitanjali Sharma et al.
Journal of controlled release : official journal of the Controlled Release Society, 167(1), 1-10 (2013-01-29)
Targeted nano-particulate systems hold extraordinary potential for delivery of therapeutics across blood brain barrier (BBB). In this work, we investigated the potential of novel bi-ligand (transferrin-poly-l-arginine) liposomal vector for delivery of desired gene to brain, in vivo. The in vivo
Dimitris Tsiourvas et al.
Journal of colloid and interface science, 384(1), 61-72 (2012-07-27)
Biodegradable oligolysine and oligoarginine-type homopeptides functionalized with PEG of two different molecular weights interact with insulin, at physiological pH, affording complexes studied by dynamic light scattering, ζ-potential, circular dichroism, FTIR spectroscopy, and isothermal titration calorimetry (ITC). High levels of insulin
Giovanni Sansoè et al.
Clinical science (London, England : 1979), 125(2), 67-75 (2013-02-07)
In rats with experimental liver cirrhosis, the kidney contains reduced amounts of membrane-bound CaRs (calcium-sensing receptors), and the specific stimulation of CaRs causes the generation of PGE2 (prostaglandin E2), renal vasodilation and increased natriuresis. CaR content and function in the
Kentaro Yomogida et al.
Biochemical and biophysical research communications, 434(2), 263-267 (2013-04-02)
Foxp3 is the master transcription factor for T regulatory (Treg) cell differentiation and function. This study aimed to test the therapeutic potential of cell penetrating recombinant Foxp3 protein in arthritis. Recombinant Foxp3 protein was fused to a cell penetrating polyarginine
Ugutz Unzueta et al.
Biomaterials, 33(33), 8714-8722 (2012-09-08)
Controlling the self-assembling of building blocks as nanoscale entities is a requisite for the generation of bio-inspired vehicles for nanomedicines. A wide spectrum of functional peptides has been incorporated to different types of nanoparticles for the delivery of conventional drugs
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