P7758
Phospholipase D from cabbage
Type I, suitable for transferase applications, lyophilized powder, ≥150 units/mg solid
Synonym(s):
Lecithinase D, Phosphatidylcholine phosphatidohydrolase, Phospholipase D from white cabbage
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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-639-8
MDL number:
type
Type I
form
lyophilized powder
specific activity
≥150 units/mg solid
composition
Protein, ~40%
suitability
suitable for transferase applications
storage temp.
−20°C
Biochem/physiol Actions
Hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid.
Analysis Note
Protein determined using biuret, unless otherwise indicated.
Other Notes
One unit will liberate 1.0 μM of choline from L-α-phosphatidylcholine (egg yolk) per hr at pH 5.6 at 30°C.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Transphosphatidylation by phospholipase D.
S F Yang et al.
The Journal of biological chemistry, 242(3), 477-484 (1967-02-10)
Milya Davlieva et al.
Antimicrobial agents and chemotherapy, 57(1), 289-296 (2012-11-02)
Daptomycin (DAP) resistance in enterococci has been linked to mutations in genes that alter the cell envelope stress response (CESR) (liaFSR) and changes in enzymes that directly affect phospholipid homeostasis, and these changes may alter membrane composition, such as that
Viviana Trezza et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(43), 14899-14908 (2012-10-27)
The brain endocannabinoid system plays a crucial role in emotional processes. We have previously identified an important role for endocannabinoids in social play behavior, a highly rewarding form of social interaction in adolescent rats. Here, we tested the hypothesis that
Anna O Müller et al.
Chemistry and physics of lipids, 165(7), 787-793 (2012-10-13)
Cardiolipin (CL) and related diphosphatidyl lipids are hardly accessible because of the complexity of their chemical synthesis. In the present paper, the transphosphatidylation reaction catalyzed by phospholipase D (PLD) from Streptomyces sp. has been proven as an alternative enzyme-assisted strategy
Jonathan J Ipsaro et al.
Nature, 491(7423), 279-283 (2012-10-16)
PIWI-family proteins and their associated small RNAs (piRNAs) act in an evolutionarily conserved innate immune mechanism to provide essential protection for germ-cell genomes against the activity of mobile genetic elements. piRNA populations comprise a molecular definition of transposons, which permits
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